Results 41 to 50 of about 3,229,514 (309)

Approximating a similarity matrix by a latent class model: A reappraisal of additive fuzzy clustering [PDF]

, 2009
Let Q be a given n×n square symmetric matrix of nonnegative elements between 0 and 1, similarities. Fuzzy clustering results in fuzzy assignment of individuals to K clusters.
Braak, C.J.F., ter, Kourmpetis, Y.I.A., Kiers, H.A.L., Bink, M.C.A.M.   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

poLCA: An R Package for Polytomous Variable Latent Class Analysis

Journal of Statistical Software, 2011
poLCA is a software package for the estimation of latent class and latent class regression models for polytomous outcome variables, implemented in the R statistical computing environment. Both models can be called using a single simple command line.
Drew A. Linzer, Jeffrey B. Lewis
doaj  

Uncovering eHealth Engagement Patterns Through Latent Class Analysis and SHAP: A Data Mining Perspective on Telehealth Access

Information
Understanding how patients engage with digital health technologies is critical for improving the reach and equity of telehealth services. While prior research has largely focused on demographic predictors of telehealth use, this study applies a hybrid ...
Ning Yang, Xin Yang
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Assessing preferences for mountain wine and viticulture by using a best-worst scaling approach: do mountains really matter for Italians?

Wine Economics and Policy, 2022
European Commission has recently published the rules on the use of the quality term "mountain product". The new regulation aims to promote the sustainable development of mountain areas and to facilitate the identification of mountain products by ...
Mikael Oliveira Linder, Katia Laura Sidali, Christian Fischer, Valerie Bossi Fedrigotti, Diego Begalli, Gesa Busch   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Patterns of physical activity in sedentary older individuals with type 2 diabetes

Clinical Diabetes and Endocrinology, 2018
Background The Community Healthy Activities Model Program for Seniors (CHAMPS) survey, summarized into weekly caloric expenditures, is a common physical activity (PA) assessment tool among older adults.
Pearl G. Lee, Jinkyung Ha, Caroline S. Blaum, Kimberlee Gretebeck, Neil B. Alexander   +4 more
doaj   +1 more source

Perceived COVID-19 threat, perceived healthcare system inequities, personal experiences of healthcare discrimination and their associations with COVID-19 preventive behavioral intentions among college students in the U.S.

BMC Public Health, 2022
College students are often reluctant to follow U.S. preventive guidelines to lower their risk of COVID-19 infection, despite an increased risk of transmission in college settings. Prior research suggested that college students who perceived greater COVID-
Juliana S. Sherchan, Jessica R. Fernandez, Shan Qiao, Arie W. Kruglanski, Allana T. Forde   +4 more
doaj   +1 more source