Results 51 to 60 of about 3,229,514 (309)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Smallholder Fish Farmers’ Preferences for Climate‐Smart Aquaculture Practices in Kakamega County, Kenya: A Latent Class Approach

open access: yesAquaculture, Fish and Fisheries
Aquaculture, identified as a critical sector to bridge the fish supply gap, remains extensively vulnerable to the vagaries of climate change. In efforts to achieve a “triple win” effect on increased productivity, enhanced resilience and reduced emissions,
Boke Christopher Magesi   +2 more
doaj   +1 more source

A latent class analysis of co-occurring insomnia and anxiety among Chinese pregnant women

open access: yesJournal of Psychosomatic Obstetrics and Gynecology
Currently, there remains a paucity of comprehensive evidence concerning the concurrent presence of insomnia and anxiety in pregnant women. This study, employing convenience sampling, enrolled 1049 Chinese pregnant women.
ShanYan Liu   +6 more
doaj   +1 more source

Mixture Rasch Model with Main and Interaction Effects of Covariates on Latent Class Membership

open access: yesInternational Journal of Assessment Tools in Education, 2019
Covariateshave been used in mixture IRT models to help explain why examinees are classedinto different latent classes. Previous research has considered manifestvariables as covariates in a mixture Rasch analysis for prediction of groupmembership.
Tugba Karadavut   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Latent class analysis of co-morbidity in the Adult Psychiatric Morbidity Survey in England 2007 : implications for DSM-5 and ICD-11 [PDF]

open access: yes, 2011
Background. Psychiatric co-morbidity is complex and ubiquitous. Our aim was to describe the extent, nature and patterning of psychiatric co-morbidity within a representative sample of the adult population of England, using latent class analysis ...
Exeter, D.   +11 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Five-latent-class model: Probability of positive perceptions for each subgroup.

open access: yes, 2021
Five-latent-class model: Probability of positive perceptions for each subgroup.
Stephanie Aboueid (5258609)   +3 more
core   +1 more source

Variations in adolescents’ motivational characteristics across gender and physical activity patterns: A latent class analysis approach

open access: yesBMC Public Health, 2017
Background Neglecting to take account of the underlying context or type of physical activity (PA) that underpins overall involvement has resulted in a limited understanding of adolescents’ PA participation.
Margaret Lawler   +2 more
doaj   +1 more source

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