Results 51 to 60 of about 5,459,614 (334)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Automated vehicle collisions in California: Applying Bayesian latent class model
, 2020 The emerging technology of automated vehicles (AV) has been rapidly advancing and is accompanied by various positive and negative potentials. The new technology is expected to affect costs mainly by reducing the number of collisions and travel time, as ...
Subasish Das +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Wine Economics and Policy, 2022 European Commission has recently published the rules on the use of the quality term "mountain product". The new regulation aims to promote the sustainable development of mountain areas and to facilitate the identification of mountain products by ...
Mikael Oliveira Linder +5 more
doaj +1 more source
Frontiers in Psychology, 2019 Background: Latent class analysis (LCA) can be used to identify subgroups of children with similar patterns of mental health symptoms and/or strengths. The method is becoming more commonly used in child mental health research, but there are reservations ...
Kimberly J. Petersen +2 more
semanticscholar +1 more source
Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung +190 more
wiley +1 more source
InformationUnderstanding how patients engage with digital health technologies is critical for improving the reach and equity of telehealth services. While prior research has largely focused on demographic predictors of telehealth use, this study applies a hybrid ...
Ning Yang, Xin Yang
doaj +1 more source
Patterns of physical activity in sedentary older individuals with type 2 diabetes
Clinical Diabetes and Endocrinology, 2018 Background The Community Healthy Activities Model Program for Seniors (CHAMPS) survey, summarized into weekly caloric expenditures, is a common physical activity (PA) assessment tool among older adults.
Pearl G. Lee +4 more
doaj +1 more source
Item selection by Latent Class-based methods [PDF]
, 2014 The evaluation of nursing homes is usually based on the administration of questionnaires made of a large number of polytomous items. In such a context, the Latent Class (LC) model represents a useful tool for clustering subjects in homogenous groups ...
Bartolucci, Francesco +2 more
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