Results 41 to 50 of about 21,533,267 (299)

Latent class growth analysis procedure and model fit.

open access: yes, 2019
Latent class growth analysis procedure and model fit.
Jaap van Weeghel (532144)   +4 more
core   +1 more source

Five-latent-class model: Probability of positive perceptions for each subgroup.

open access: yes, 2021
Five-latent-class model: Probability of positive perceptions for each subgroup.
Stephanie Aboueid (5258609)   +3 more
core   +1 more source

Measuring the performance of LPA, LCGA, LGCM, and GMM in identifying the homogenous subgroups (latent classes) within the wider heterogeneous population of patients on DTG

open access: yesFrontiers in Applied Mathematics and Statistics
BackgroundIdentifying heterogeneity in longitudinal data is critical for understanding diverse trajectories in clinical and epidemiological research. Traditional analytical methods often fail to distinguish latent subpopulations.
Harrid Nkhoma   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

The dynamics of adolescents’ pornography use and psychological well-being: a six-wave latent growth and latent class modeling approach

open access: yesEuropean Child & Adolescent Psychiatry, 2019
Despite increasing concerns that pornography decreases adolescents' well-being, existing empirical support for this position is largely limited to cross-sectional studies. To explore possible links between adolescent pornography use and psychological well-being more systematically, this study focused on parallel dynamics in pornography use, self-esteem
Štulhofer, Aleksandar   +2 more
  +5 more sources

Model fit criteria comparing 1-class, 2-class, 3-class latent class analysis model.

open access: yes, 2022
Model fit criteria comparing 1-class, 2-class, 3-class latent class analysis model.
Eric Zhu (4178614)   +3 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Piecewise modeling for longitudinal psychological research: a tutorial using R

open access: yesFrontiers in Psychology
Longitudinal psychological research often centers on key developmental transitions, where patterns of change may differ across stages. Piecewise modeling is well suited to capturing these stage-specific changes.
Shuncheng He, Wooyeol Lee
doaj   +1 more source

A bootstrap approach for validating the number of groups identified by latent class growth models

open access: yes, 2022
The use of longitudinal finite mixture models such as group-based trajectory modeling has seen a sharp increase during the last decades in the medical literature. However, these methods have been criticized especially because of the data-driven modelling process which involves statistical decision-making. In this paper, we propose an approach that uses
Mésidor, Miceline   +3 more
openaire   +2 more sources

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