Results 31 to 40 of about 9,468,510 (297)
JMIR Medical Informatics, 2022 BackgroundHealth care organizations are collecting increasing volumes of clinical text data. Topic models are a class of unsupervised machine learning algorithms for discovering latent thematic patterns in these large unstructured
Christopher Meaney +4 more
doaj +1 more source
A New Formulation for Latent Class Models [PDF]
SSRN Electronic Journal, 2014 Latent class, or finite mixture, modelling has proved a very popular, and relatively easy, way of introducing much-needed heterogeneity into empirical models right across the social sciences. The technique involves (probabilistically) splitting the population into a finite number of (relatively homogeneous) classes, or types.
Sarah Brown +2 more
openaire +4 more sources
Engineering Reports, 2022 It is known that how individuals perceive the situation result in choices. However, it is unknown, how drivers process the information of vehicle malfunctions based on the situation at hand.
Mahdi Rezapour, Khaled Ksaibati
doaj +1 more source
Bayesian latent variable models for collaborative item rating prediction [PDF]
, 2011 Collaborative filtering systems based on ratings make it easier for users to find content of interest on the Web and as such they constitute an area of much research.
Harvey, Morgan Alexander +3 more
core +4 more sources
BMC Bioinformatics, 2011 Background Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1 million genetic markers) and its complexity make the statistical analysis a
Leray Philippe +2 more
doaj +1 more source
Latent Structure Models for Analyzing Processes of Change a General Framework and a Latent Class Markov Chain Model [PDF]
The Egyptian Statistical Journal, 1992 This paper is a continuation and development of work on a group of latent structure models proposed by Lazarsfeld and Henry (1968) and Wiggins (1973) for analyzing processes of change over time. There have been problems associated with these models, see,
Hatem Abdel-Aty
doaj +1 more source
Analysis and modeling of trucks travel choice preference under differentiated charging
Shenzhen Daxue xuebao. Ligong ban, 2023 To study the impact of expressway differentiated charging on the travel choice behavior of truck drivers, this paper combines the multinomial logit (MNL) model, the nested logit (NL) model and the latent class model based on the theoretical framework of ...
KONG Dexue +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source