Results 231 to 240 of about 115,334 (309)

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček   +3 more
wiley   +1 more source

Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti‐inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Adenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Nusrat Jahan Moon   +10 more
wiley   +1 more source

Effect of fins in enhancing phase change material fusion in a spherical thermal energy storage container. [PDF]

open access: yesSci Rep
Swami Punniakodi BM   +7 more
europepmc   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

open access: yesAnnals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian   +9 more
wiley   +1 more source

Engineering Binary Metal Oxide Nano‐Oscillators for Deterministic and Probabilistic Computing: From Material Physics to Emerging Paradigms

open access: yesAdvanced Physics Research, EarlyView.
This study demonstrates a versatile hardware platform using nano‐oscillators based on binary oxides for deterministic and probabilistic computing. By tailoring material physics, NbOx enables energy‐efficient synchronization for pattern recognition, while enhanced stochasticity in engineered SiOx provides robust entropy for p‐bits to solve complex ...
Jihyun Kim   +3 more
wiley   +1 more source

Thermal management of lithium-ion batteries: from single cooling to hybrid cooling. [PDF]

open access: yesRSC Adv
Qianqian Z   +6 more
europepmc   +1 more source

T. rex cognition was T. rex‐like—A critical outlook on diverging views of the neurocognitive evolution in dinosaurs

open access: yesThe Anatomical Record, EarlyView.
Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen   +7 more
wiley   +1 more source

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