Results 11 to 20 of about 84,072 (248)

Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines [PDF]

Retrovirology, 2011
Background Molecular adjuvants are a promising method to enhance virus-specific immune responses and protect against HIV-1 infection. Immune activation by ligands for receptors such as CD40 can induce dendritic cell activation and maturation.
Rahmberg Andrew R, Kanagavelu Saravana K, Niu Liguo, Termini James M, Gupta Sachin, Kornbluth Richard S, Evans David T, Stone Geoffrey W   +7 more
doaj   +4 more sources

Epstein-Barr virus latent membrane protein-1 expression in Hodgkin lymphoma

Bangabandhu Sheikh Mujib Medical University Journal, 2018
Expression of latent membrane protein-1 of Epstein-Barr virus is documented in Hodgkin lymphoma indicating its relationship in disease process.
Ferdousy Begum, Prabir Kumar Saha, Tasmina Enam, Mohammed Kamal   +3 more
doaj   +2 more sources

Latent Membrane Protein 1 Is a Novel Determinant of Epstein-Barr Virus Genome Persistence and Reactivation [PDF]

mSphere, 2017
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus that persistently infects humans, with nearly 95% seropositivity in adults. Infection in differentiating epithelia is permissive, but EBV-associated nasopharyngeal carcinoma (NPC) tumors harbor a ...
Elizabeth A. Caves, Rachel M. Butch, Sarah A. Cook, Laura R. Wasil, Chen Chen, Yuanpu Peter Di, Nara Lee, Kathy H. Y. Shair   +7 more
doaj   +2 more sources

Global Proteomic Changes Induced by the Epstein-Barr Virus Oncoproteins Latent Membrane Protein 1 and 2A [PDF]

mBio, 2018
The Epstein-Barr virus (EBV) oncoproteins latent membrane protein 1 (LMP1) and LMP2A constitutively activate multiple signaling pathways, and both have been shown to interact with cellular ubiquitin ligases and affect cellular ubiquitination.
Robert M. DeKroon, Harsha P. Gunawardena, Rachel Edwards, Nancy Raab-Traub   +3 more
doaj   +2 more sources

Deciphering the Role of Epstein–Barr Virus Latent Membrane Protein 1 in Immune Modulation: A Multifaced Signalling Perspective [PDF]

Viruses
The disruption of antiviral sensors and the evasion of immune defences by various tactics are hallmarks of EBV infection. One of the EBV latent gene products, LMP1, was shown to induce the activation of signalling pathways, such as NF-κB, MAPK (JNK, ERK1/
Petra Šimičić, Margarita Batović, Anita Stojanović Marković, Snjezana Židovec-Lepej   +3 more
doaj   +2 more sources

Exposure to the Epstein–Barr Viral Antigen Latent Membrane Protein 1 Induces Myelin-Reactive Antibodies In Vivo [PDF]

Frontiers in Immunology, 2017
Multiple sclerosis (MS) is an autoimmune chronic inflammatory disease of the central nervous system (CNS). Cross-reactivity of neuronal proteins with exogenous antigens is considered one of the possible mechanisms of MS triggering.
Yakov Lomakin, Yakov Lomakin, Georgii Pavlovich Arapidi, Georgii Pavlovich Arapidi, Alexander Chernov, Rustam Ziganshin, Evgenii Tcyganov, Irina Lyadova, Ivan Olegovich Butenko, Maria Osetrova, Natalia Ponomarenko, Georgy Telegin, Vadim Markovich Govorun, Vadim Markovich Govorun, Vadim Markovich Govorun, Alexander Gabibov, Alexander Gabibov, Alexander Gabibov, Alexey Belogurov, Alexey Belogurov, Alexey Belogurov   +20 more
doaj   +2 more sources

Prognostic significance of latent membrane protein 1 expression in non-Hodgkin lymphoma: A meta-analysis. [PDF]

Medicine (Baltimore), 2017
The prognostic value of latent membrane protein 1 (LMP1) in non-Hodgkin lymphoma (NHL) has been evaluated in several studies. However, the conclusions remain controversial.We searched relevant literatures from Embase, PubMed, and China National Knowledge Infrastructure Platform databases and performed a meta-analysis to evaluate the prognostic ...
Li XM, Xiao WH, Zhao HX.
europepmc   +3 more sources

Analysis of the association between Epstein Barr virus infection and Hodgkin lymphoma

Bangabandhu Sheikh Mujib Medical University Journal, 2023
Epstein Barr virus plays an important role in the pathogenesis of Hodgkin lymphoma. However, the frequency of its association in Bangladeshi people has not been widely studied. The aim of this study was to determine the association of Epstein Barr virus
Jasmine Akhter Jahan, S M Rashed Ul Islam, Md Shafikul Alam Tanim, Tasnim Binte Ahmed, Md Rabiul Alam, Ferdousy Begum   +5 more
doaj   +5 more sources

Evaluation of plasma Epstein–Barr virus DNA as a biomarker for Epstein–Barr virus–associated Hodgkin lymphoma

SAGE Open Medicine, 2021
Objectives: Epstein–Barr virus is a tumorigenic virus and has been extensively studied as a causative agent for Hodgkin lymphoma. Although immunostaining of the tumor biopsy is the standard method for diagnosis of Epstein–Barr virus-driven Hodgkin ...
Masuma Khatun Usha, Jasmine Akhter Jahan, SM Rashed Ul Islam, Ferdousy Begum, Chowdhury Rafiqul Ahsan, Mahmuda Yasmin   +5 more
doaj   +1 more source

Epstein-Barr Virus Represses the FoxO1 Transcription Factor through Latent Membrane Protein 1 and Latent Membrane Protein 2A [PDF]

Journal of Virology, 2006
ABSTRACT Epstein-Barr virus (EBV) infection is associated with the development of many B-cell lymphomas, including Burkitt's lymphoma, Hodgkin's lymphoma, and posttransplant lymphoproliferative disease. The virus alters a diverse range of cellular molecules, which leads to B-cell growth and immortalization.
Shore, Angharad M, White, Paul C, Hui, Rosaline C-Y, Essafi, Abdelkader, Lam, Eric W-F, Rowe, Martin, Brennan, Paul   +6 more
openaire   +3 more sources