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Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review

JEADV Clinical Practice, EarlyView.
Miranda K. Branyiczky, Megan Lowe, Eric McMullen, Shireen Dumont, Narachai Julanon, Vincent Piguet, Cathryn Sibbald   +6 more
wiley   +1 more source

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The Latent Membrane Protein 1 (LMP1)

2015
Almost exactly twenty years after the discovery of Epstein-Barr virus (EBV), the latent membrane protein 1 (LMP1) entered the EBV stage, and soon thereafter, it was recognized as the primary transforming gene product of the virus. LMP1 is expressed in most EBV-associated lymphoproliferative diseases and malignancies, and it critically contributes to ...
Kieser, A., Sterz, K.
openaire   +3 more sources

Latent Membrane Protein 1 and the B Lymphocyte-A Complex Relationship

Critical Reviews in Immunology, 2014
The Epstein Barr Virus (EBV)-encoded latent membrane protein 1 (LMP1) exerts numerous impacts on the functions of B lymphocytes, the cell type in which EBV establishes long-term latent infections. LMP1 expression has been implicated in making important contributions to a variety of human malignancies, as well as to autoimmune diseases. EBV also infects
Laura L, Stunz, Gail A, Bishop
openaire   +2 more sources

Assembly and activation of EBV latent membrane protein 1

Cell
Latent membrane protein 1 (LMP1) is the primary oncoprotein of Epstein-Barr virus (EBV) and plays versatile roles in the EBV life cycle and pathogenesis. Despite decades of extensive research, the molecular basis for LMP1 folding, assembly, and activation remains unclear.
Jiafeng Huang, Xiaolin Zhang, Xiaohua Nie, Xuyuan Zhang, Yong Wang, Linlong Huang, Xiaohan Geng, Dong Li, Liguo Zhang, Guangxia Gao, Pu Gao   +10 more
openaire   +2 more sources

Insights into intricacies of the Latent Membrane Protein-1 (LMP-1) in EBV-associated cancers

Life Sciences, 2023
Numerous lymphomas, carcinomas, and other disorders have been associated with Epstein-Barr Virus (EBV) infection. EBV's carcinogenic potential can be correlated to latent membrane protein 1 (LMP1), which is essential for fibroblast and primary lymphocyte transformation.
Prankur Awasthi, Manish Dwivedi, Dhruv Kumar, Saba Hasan   +3 more
openaire   +2 more sources

Latent Membrane Protein-1 Oncogene Deletions in Nasopharyngeal Carcinoma in Caucasian Patients

Acta Oto-Laryngologica, 2003
The latent membrane protein-1 (LMP-1) is an Epstein-Barr virus (EBV)-transforming protein expressed in nasopharyngeal carcinoma (NPC). A 30-bp deletion in the LMP-1 oncogene has been described in NPC patients from Asia. The purpose of this study was to evaluate the association between NPC and such an EBV deletion in Caucasian patients.Twenty-seven ...
Guillermo, Plaza, Almudena, Santón, Antonio Martínez, Vidal, Carmen, Bellas   +3 more
openaire   +2 more sources

[Latent membrane protein LMP-1 in Hodgkin's lymphoma].

Vnitrni lekarstvi, 2000
The authors examined using the antibody against latent membrane protein (LMP-1) a group of 169 patients with Hodgkin's lymphoma (age 2 to 82 years). From the total number of 169 patients 48 (28%) patients were positive when tested with this antibody. In the whole group the following histological types were represented most frequently: type II (nodular ...
J, Macák, L, Plank, B, Habanec, P, Fabian   +3 more
openaire   +1 more source

Plasma Membrane Proteomic Profile Discovers Macrophage-capping Protein Related to Latent HIV-1

Current HIV Research, 2019
Background:Due to the persistence of latent HIV-infected cellular reservoirs, HIV virus can not be eradicated completely.Objective:To identify proteins related to HIV latency, we performed a subcellular proteomic study in HIV latent cell lines.Method:An established HIV-1 latent cell model (J-Lat Tat-GFP Clone A7 cells, A7 cells) and its parental cell ...
Yujiao Zhang, Yinzhong Shen, Lin Yin, Tangkai Qi, Xiaofang Jia, Hongzhou Lu, Lijun Zhang   +6 more
openaire   +2 more sources

Ubiquitination of MDM2 modulated by Epstein-Barr virus encoded latent membrane protein 1

Virus Research, 2007
Epstein-Barr virus encoded latent membrane protein 1 (LMP1), an oncogenic protein, plays an important role in the carcinogenesis of nasopharyngeal carcinoma. The MDM2 gene is a cellular pro-oncogene that is abnormally up-regulated in human tumors.
Lili, Li, Zijian, Li, Shanghui, Zhou, Lanbo, Xiao, Lili, Guo, Yongguang, Tao, Min, Tang, Ying, Shi, Wei, Li, Wei, Yi, Ya, Cao   +10 more
openaire   +2 more sources

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly