Results 121 to 130 of about 99,241 (260)

Heterogeneity in nurses' attitudes toward artificial intelligence: a latent profile analysis. [PDF]

BMC Health Serv Res
Li X, Xu H, Hu X, Guo J, Yu P, Ju H.
europepmc   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Latent profile analysis of adolescents' active health behaviors and the predictive factors. [PDF]

Sci Rep
Zhang Z, Xu Y, Jin J, Xuan Y, Shen X.
europepmc   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

A Latent Profile Analysis of Psychological Adaptation Among Caregivers of Children with Strabismus: A Cross-Sectional Study

Journal of Multidisciplinary Healthcare
Yawen Mo,1,* Xueke Wang,2,* Manli Zhou,1 Chunying Dai,1 Haimin Zeng,1 Yue Cai,2 Yinghuan Wang1 1Department of Strabismus and Amblyopia, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong ...
Mo Y, Wang X, Zhou M, Dai C, Zeng H, Cai Y, Wang Y   +6 more
doaj  

Sleep Quality Profiles in Youth with Eating Disorders: A Latent Profile Analysis. [PDF]

Brain Sci
Carbone EA, Aloi M, de Filippis R, Rania M, Scordo A, Procopio C, Rotella L, Quirino D, D'Onofrio E, De Fazio P, Segura-Garcia C.   +10 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

A latent profile analysis of Germans' threat perceptions, intergroup emotions and attitudes toward refugees. [PDF]

BMC Psychol
Schubert S, Kluge U, Hess U, Ringeisen T.   +3 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Latent Profile Analysis of Emotional Expression Conflicts and Associated Influencing Factors in Breast Cancer Patients Receiving Postoperative Chemotherapy

Cancer Management and Research
Zhaoxia Tian,* Ruishan Sheng,* Yutong Zhang, Hongmei Li Department of Nursing, Fenyang College of Shanxi Medical University, Fenyang City, Shanxi Province, People’s Republic of China*These authors contributed equally to this ...
Tian Z, Sheng R, Zhang Y, Li H
doaj