Results 261 to 270 of about 679,297 (329)

Characterizing the distribution of Chinese medicine syndrome of cancer-related fatigue in childhood lymphoma based on latent structure model. [PDF]

J Tradit Chin Med
Ziqi D, Jing H, Lu LU, Yuru C, Guoling G, Yanlong D, Ling J, Shuang H, Meng Z, Nan LI, Zhen G, Jiaxuan L.   +11 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Bayesian Sensitivity Analysis for Causal Estimation With Time-Varying Unmeasured Confounding. [PDF]

Stat Med
Zou Y, Hu L, Ricciuto A, Deneau M, Liu K.   +4 more
europepmc   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

The Impact of Latent Density Misspecification on Item Response Theory Equating Methods. [PDF]

Appl Psychol Meas
Kim KY, Kim S, Lee H.
europepmc   +1 more source

Latent Variable Models for Indirectly or Imprecisely Measured Networks

, 2019
Wesley Lee
openalex   +1 more source

DYNAMIC CLASSIFICATION OF LATENT DISEASE PROGRESSION WITH AUXILIARY SURROGATE LABELS. [PDF]

Ann Appl Stat
Cai Z, Zeng D, Marder KS, Honig LS, Wang Y.   +4 more
europepmc   +1 more source

Comparing Bayesian random coefficient prediction and latent interaction models for multilevel moderated mediation. [PDF]

Front Psychol
Lee S, Kim S.
europepmc   +1 more source

A study on the motivation stratification and behavioral differentiation patterns of sports socializing among Chinese residents: an empirical exploration based on latent profile analysis and random forest models. [PDF]

BMC Public Health
Tian Y, Liu S, Zhao F.
europepmc   +1 more source