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Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
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Burn‐Safe Biodegradable Magnetocaloric Composites for Temperature‐Controlled Biomedical Applications
Advanced Science, EarlyView.This work investigates a magnetocaloric (Mn,Fe)2(P,Si) compound tailored for precise, self‐regulating heating in biomedical use. With a Curie temperature tuned at 43 °C, it enables therapeutic activation without overheating. Encapsulation in a composite ensures controlled temperature rise under an alternating magnetic field (AMF), with high ...
Pornpawee Uliss +8 more
wiley +1 more source
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Catalysis from A to Z, 2020
In the social sciences, we attempt to measure many phenomena that are not directly observable (or, at least, not directly observed). The true variable or construct of interest is not precisely the one that is measured. A simple example is the measurement
semanticscholar +1 more source
In the social sciences, we attempt to measure many phenomena that are not directly observable (or, at least, not directly observed). The true variable or construct of interest is not precisely the one that is measured. A simple example is the measurement
semanticscholar +1 more source
Measurement: Interdisciplinary Research & Perspective, 2008
This paper formulates a metatheoretical framework for latent variable modeling. It does so by spelling out the difference between observed and latent variables. This difference is argued to be purely epistemic in nature: We treat a variable as observed when the inference from data structure to variable structure can be made with certainty and as latent
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This paper formulates a metatheoretical framework for latent variable modeling. It does so by spelling out the difference between observed and latent variables. This difference is argued to be purely epistemic in nature: We treat a variable as observed when the inference from data structure to variable structure can be made with certainty and as latent
openaire +3 more sources
Behavioral and Brain Sciences, 2010
AbstractIn the target article, Cramer et al. suggest that diagnostic classification is improved by modeling the relationship between manifest variables (i.e., symptoms) rather than modeling unobservable latent variables (i.e., diagnostic categories such as Generalized Anxiety Disorder).
Dennis J, McFarland, Loretta S, Malta
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AbstractIn the target article, Cramer et al. suggest that diagnostic classification is improved by modeling the relationship between manifest variables (i.e., symptoms) rather than modeling unobservable latent variables (i.e., diagnostic categories such as Generalized Anxiety Disorder).
Dennis J, McFarland, Loretta S, Malta
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Latent variable models with nonparametric interaction effects of latent variables
Statistics in Medicine, 2013Renal disease is one of the common complications of diabetes, especially for Asian populations. Moreover, cardiovascular and renal diseases share common risk factors. This paper proposes a latent variable model with nonparametric interaction effects of latent variables for a study based on the Hong Kong Diabetes Registry, which was established in 1995 ...
Song, Xinyuan +2 more
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Building latent variable models
1991Department of Philosophy technical ...
Scheines, Richard +2 more
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