Results 111 to 120 of about 1,279,508 (285)

GABAC receptors in the lateral amygdala: a possible novel target for the treatment of fear and anxiety disorders?

open access: yesFrontiers in Behavioral Neuroscience, 2010
Activation of GABAARs in the lateral nucleus of the amygdala (LA), a key site of plasticity underlying fear learning, impairs fear learning. The role of GABACRs in the LA and other brain areas is poorly understood.
Catarina Cunha   +5 more
doaj   +1 more source

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Effects of Noninvasive Cervical Vagal Nerve Stimulation on Cognitive Performance But Not Brain Activation in Healthy Adults

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2020
Abstract Objectives While preliminary evidence suggests that noninvasive vagal nerve stimulation (nVNS) may enhance cognition, to our knowledge, no study has directly assessed the effects of nVNS on brain function and cognitive performance in healthy individuals.
Ruth Klaming   +3 more
wiley   +1 more source

Epilepsy surgery: From bench to the clinics

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Semiology in spontaneous versus cortical stimulation‐induced seizures during SEEG: A within‐patient comparison study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective We aimed to study the concordance of seizure semiology in direct electrical stimulation‐induced seizures (SIS) compared to spontaneous seizures during stereoelectroencephalography (SEEG) and to report on patient‐level variables associated with habitual and atypical SIS.
Marai Mahizhnan   +5 more
wiley   +1 more source

Amygdala Neurodegeneration: A Key Driver of Visual Dysfunction in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology
Objective Visual disability in Parkinson's disease (PD) is not fully explained by retinal neurodegeneration. We aimed to delineate the brain substrate of visual dysfunction in PD and its association with retinal thickness.
Asier Erramuzpe   +15 more
doaj   +1 more source

Inhibitory fear memory engram in the mouse central lateral amygdala

open access: yesCell Reports
Engrams, which are cellular substrates of memory traces, have been identified in various brain areas, including the amygdala. While most identified engrams are composed of excitatory, glutamatergic neurons, GABAergic inhibitory engrams have been relatively overlooked.
Wen-Hsien Hou   +9 more
openaire   +2 more sources

Neuropsychological profile and social cognition in children and adolescents with temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To characterize the neuropsychological profile and social cognition, particularly Theory of Mind (ToM), in 45 children and adolescents with temporal lobe epilepsy (TLE) compared with 56 age, gender, and schooling‐matched healthy controls.
Claudia Accolla   +5 more
wiley   +1 more source

Structural brain imaging biomarkers for predicting seizure recurrence after a first unprovoked seizure

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Predicting seizure recurrence following a first unprovoked seizure (FUS) remains a significant clinical challenge, especially when routine clinical magnetic resonance imaging (MRI) and EEG do not reveal abnormalities diagnostic of epilepsy.
Suyi Ooi   +7 more
wiley   +1 more source

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