Results 101 to 110 of about 156,525 (292)

Cultural imagery and statistical models of the force of mortality: Addison, Gompertz and Pearson [PDF]

, 2010
We describe selected artistic and statistical depictions of the force of mortality (hazard or mortality rate), which is a concept that has long preoccupied actuaries, demographers and statisticians.
Hanley, JA, Turner, EL
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Enabling In‐House Fabrication of Lateral Flow Assays With a Low‐Cost DIY Antibody Dispenser

Advanced Sensor Research
Lateral flow assays (LFAs) are versatile detection devices widely used in various fields including healthcare, agriculture, and waste surveillance.
Laura M. Rey Gomez, Rena Hirani, Andrew Care, Yuling Wang, David W. Inglis   +4 more
doaj   +1 more source

Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]

, 2017
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann, Dubberke, Erik, Franklin, Alexander, Lainhart, William, O\u27Halloran, Jane A, Powderly, William   +5 more
core   +2 more sources

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Development of sandwich ELISA and lateral flow strip assays for diagnosing clinically significant snakebite in Taiwan.

PLoS Neglected Tropical Diseases, 2018
Taiwan is an island located in the south Pacific, a subtropical region that is home to 61 species of snakes. Of these snakes, four species-Trimeresurus stejnegeri, Protobothrops mucrosquamatus, Bungarus multicinctus and Naja atra-account for more than 90%
Chien-Chun Liu, Jau-Song Yu, Po-Jung Wang, Yung-Chin Hsiao, Chien-Hsin Liu, Yen-Chia Chen, Pei-Fang Lai, Chih-Po Hsu, Wen-Chih Fann, Chih-Chuan Lin   +9 more
doaj   +1 more source

Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration. [PDF]

, 2003
Integrins coordinate spatial signaling events essential for cell polarity and directed migration. Such signals from alpha4 integrins regulate cell migration in development and in leukocyte trafficking.
Ginsberg, Mark H, Goldfinger, Lawrence E, Han, Jaewon, Howe, Alan K, Kiosses, William B   +4 more
core   +1 more source

Isothermal Recombinase Polymerase amplification (RPA) of Schistosoma haematobium DNA and oligochromatographic lateral flow detection [PDF]

, 2015
© 2015 Rosser et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in ...
A Ahmed, A. Rosser, AM Emery, B L Webster, BB Obeng, C Escadafal, C Shiff, CH King, D Rollinson, D Rollinson, D Wichmann, D. Rollinson, EF Kjetland, F Amarir, JR Stothard, JR Stothard, JS McCarthy, K Krolov, L Cnops, M. Forrest, MG Cavalcanti, MJ Werf van der, N Lodh, N Nausch, NP Pai, NV Vinkeles Melchers, OP Akinwale, R Bergquist, S Kersting   +28 more
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

The Peach RGF/GLV Signaling Peptide pCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions [PDF]

, 2017
In vascular plants the cell-to-cell interactions coordinating morphogenetic and physiological processes are mediated, among others, by the action of hormones, among which also short mobile peptides were recognized to have roles as signals.
Dale F. Mierke, Fabrizio Costa, Francesca Resentini, Livio Trainotti, Lorella Navazio, Maria Pellegrini, Nicola Busatto, Nicola Busatto, Oriano Marin, Silvia Quaresimin, Umberto Salvagnin   +10 more
core   +3 more sources