We describe the detection characteristics of a device the Resonant Coil Magnetometer (RCM) to quantify paramagnetic particles (PMPs) in immunochromatographic (lateral flow) assays.
Jacqueline M. Barnett +6 more
doaj +1 more source
Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2
Background COVID-19 has resulted in significant morbidity and mortality worldwide. Lateral flow assays can detect anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) antibodies to monitor transmission.
Bianca A. Trombetta +57 more
doaj +1 more source
This paper presents a lateral flow assay (LFA) for the quantitative, fluorescence-based detection of the cardiac biomarker troponin I (cTnI) that features an analytical strip made of cellulose filter paper. The results show that the wicking and test time
Satheesh Natarajan +2 more
doaj +1 more source
Sensitive electrochemiluminescence (ECL) immunoassays for detecting lipoarabinomannan (LAM) and ESAT-6 in urine and serum from tuberculosis patients. [PDF]
BackgroundTuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to determine whether accurate TB antigen detection in blood or urine has the potential to meet the ...
Barbero, Simone +13 more
core +2 more sources
Detection of Shiga Toxins by Lateral Flow Assay [PDF]
Shiga toxin-producing Escherichia coli (STEC) produce shiga toxins (Stxs) that can cause human disease and death. The contamination of food products with STEC represents a food safety problem that necessitates rapid and effective detection strategies to mitigate risk.
Kathryn Ching +5 more
openaire +3 more sources
Development of Multiplexed Infectious Disease Lateral Flow Assays: Challenges and Opportunities
Lateral flow assays (LFAs) are the mainstay of rapid point-of-care diagnostics, with the potential to enable early case management and transform the epidemiology of infectious disease. However, most LFAs only detect single biomarkers.
Khayriyyah Mohd Hanafiah +5 more
doaj +1 more source
Evaluation of Simple Lateral Flow Immunoassays for Detection of SARS-CoV-2 Neutralizing Antibodies
Immunization for the generation of protective antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged to be highly effective in preventing hospital admission, need for intensive care treatment and high mortality in the
Olaf Nickel +3 more
doaj +1 more source
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. [PDF]
Hexanucleotide-repeat expansions in the C9ORF72 gene are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (c9ALS/FTD).
A Berson +95 more
core +1 more source
Development of colorimetric lateral flow assays with gold nanostructures for Cystatin C detection
Cystatin C (CysC) is a biomarker indicative of renal function, and its comorbidities, including heart failure. Generally, enzyme-linked immunosorbent assay (ELISA) can detect CysC in hours but requires skilled personnel, thorough reagent preparation, and
Xushuo Zhang +3 more
doaj +1 more source
Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey [PDF]
Lateral flow (immuno)assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring in resource-poor or non-laboratory environments.
Amerongen, A., van +2 more
core +1 more source

