Two target genes based multiple cross displacement amplification combined with a lateral flow biosensor for the detection of Mycobacterium tuberculosis complex. [PDF]
BMC Microbiol, 2021 Huang J +9 more
europepmc +1 more source
Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects
Interdisciplinary Medicine, EarlyView.Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou +6 more
wiley +1 more source
Development and Application of a Multiple Cross Displacement Amplification Combined With Nanoparticle-Based Lateral Flow Biosensor Assay to Detect Candida tropicalis. [PDF]
Front Microbiol, 2021 Wang Y +6 more
europepmc +1 more source
Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
Interdisciplinary Medicine, EarlyView.This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
wiley +1 more source
Development of molecular lateral flow biosensors for non-covered medical needs
, 2023 La pandèmia actual de SARS-CoV-2 ha ressaltat la importància de poder desenvolupar, produir i desplegar ràpidament proves de diagnòstic per a malalties infeccioses emergents, ja que el SARS-CoV-2 no serà l'última amenaça. A més, la prevalença creixent de la resistència als antimicrobians s'ha convertit en una pandèmia silenciosa que ja s'està cobrant ...
openaire +2 more sources
Journal of the Science of Food and Agriculture, EarlyView.Abstract Mycotoxins remain a persistent threat to the safety and quality of cereal grains and other agricultural products, and their impact on human health continues to raise global concerns. In many situations, the practices traditionally used to control these toxins are no longer sufficiently effective. They can be costly, difficult to implement on a
Abolfazl Asqardokht‐Aliabadi +2 more
wiley +1 more source
Development and Preliminary Application of Multiplex Loop-Mediated Isothermal Amplification Coupled With Lateral Flow Biosensor for Detection of Mycobacterium tuberculosis Complex. [PDF]
Front Cell Infect Microbiol, 2021 Wang X +9 more
europepmc +1 more source
Medicine Bulletin, EarlyView.The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du +10 more
wiley +1 more source
Multiple Cross Displacement Amplification Linked with Nanoparticles-Based Lateral Flow Biosensor in Screening of Hepatitis B Virus in Clinical Application. [PDF]
Infect Drug Resist, 2021 Chen X +6 more
europepmc +1 more source
Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source