Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism [PDF]
Xiaofeng Dong +9 more
openalex +1 more source
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
Genomic Analysis of MSM Rectal Chlamydia trachomatis Isolates Identifies Predicted Tissue-Tropic Lineages Generated by Intraspecies Lateral Gene Transfer-Mediated Evolution. [PDF]
Suchland RJ +7 more
europepmc +1 more source
Evaluating the role of the Hippo pathway in the onset and disease progression of the SOD1 mouse model of amyotrophic lateral sclerosis [PDF]
The Hippo pathway is a cell signaling pathway involved in organ size regulation and tumorigenesis in mammals. This pathway regulates the activity of Yes-associated protein (YAP), a transcriptional coactivator which binds to the transcription factor TEAD ...
Granucci, Eric
core +1 more source
A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova +5 more
wiley +1 more source
The Genesis of Methicillin-Resistant \u3ci\u3eStaphylococcus aureus\u3c/i\u3e: A Modern Day Leprosy and Hospital Menace [PDF]
Methicillin-Resistant Staphylococcus aureus leads to more deaths than AIDS and resists most antibiotics.
Gillen, Alan L.
core +1 more source
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou +10 more
wiley +1 more source
Chlamydia trachomatis: a model for intracellular bacterial parasitism
Chlamydia comprises a diverse group of obligate intracellular bacteria that cause infections in animals, including humans. These organisms share fascinating biology, including distinct developmental stages, non-canonical cell surface structures, and ...
Erin P. Smith, Raphael H. Valdivia
doaj +1 more source
Inter-species lateral gene transfer focused on the Chlamydia plasticity zone identifies loci associated with immediate cytotoxicity and inclusion stability. [PDF]
Dimond ZE +11 more
europepmc +1 more source
Beyond Conventional Cooling: Advanced Micro/Nanostructures for Managing Extreme Heat Flux
This review examines the design, application, and manufacturing of biomimetic or engineered micro/nanostructures for managing high heat‐flux in multi‐level electronics by enhancing conductive, convective, phase‐changing, and radiative heat transfer mechanisms, highlighting their potential for efficient, targeted thermal management, and future prospects.
Yuankun Zhang +7 more
wiley +1 more source

