Results 181 to 190 of about 219,064 (327)

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Lateral Transfer of an EF-1α Gene

, 2002
Yuji Inagaki, W. Ford Doolittle, Sandra L. Baldauf, Andrew J. Roger   +3 more
openalex   +1 more source

Lateral gene transfer between obligate intracellular bacteria: Evidence from the Rickettsia massiliae genome [PDF]

, 2007
Guillaume Blanc, Hiroyuki Ogata, Catherine Robert, Stéphane Audic, Jean‐Michel Claverie, Didier Raoult   +5 more
openalex   +1 more source

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

Advanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang, Dajun Li, Xiao Ying Li, Weizhao Lu, Huini Ding, Chengyan Qi, Xuan Wang, Jing Shen, Yafei Chi, Tiantian Li, Michelle M. Dunk, Yu An, Hongmei Huang, Kang Yu, Weili Xu, Rong Xiao, Yuandi Xi   +16 more
wiley   +1 more source

Genome expansion in early eukaryotes drove the transition from lateral gene transfer to meiotic sex. [PDF]

Elife, 2020
Colnaghi M, Lane N, Pomiankowski A.
europepmc   +1 more source

Phylogenetic analyses suggest lateral gene transfer from the mitochondrion to the apicoplast

, 2002
Miroslav Obornı́k, Yves Van de Peer, Václav Hypša, Tancred Frickey, Jan Šlapeta, Axel Meyer, Julius Lukeš   +6 more
openalex   +2 more sources

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Lateral Gene Transfer Drives Metabolic Flexibility in the Anaerobic Methane-Oxidizing Archaeal Family Methanoperedenaceae. [PDF]

mBio, 2020
Leu AO, McIlroy SJ, Ye J, Parks DH, Orphan VJ, Tyson GW.   +5 more
europepmc   +1 more source

Evidence for Lateral Transfer of Genes Encoding Ferredoxins, Nitroreductases, NADH Oxidase, and Alcohol Dehydrogenase 3 from Anaerobic Prokaryotes to Giardia lamblia and Entamoeba histolytica

, 2002
Julie Nixon, Amy Wang, Jessica Field, Hilary G. Morrison, Andrew G. McArthur, Mitchell L. Sogin, Brendan Loftus, John Samuelson   +7 more
openalex   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source