Results 201 to 210 of about 219,064 (327)

Orientia tsutsugamushi:analysis of the mobilome of a highly fragmented and repetitive genome reveals ongoing lateral gene transfer in an obligate intracellular bacterium

, 2023
Giengkam S, Kullapanich C, Wongsantichon J, Adcox HE, Gillespie JJ, Salje J.   +5 more
europepmc   +1 more source

Faculty Opinions recommendation of The source of laterally transferred genes in bacterial genomes.

, 2003
Camilla Nesbø
openalex   +1 more source

Microbial co-habitation and lateral gene transfer: what transposases can tell us [PDF]

, 2009
Sean Hooper, Konstantinos Mavromatis, Nikos C. Kyrpides   +2 more
openalex   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Chromosomal Recombination Targets in Chlamydia Interspecies Lateral Gene Transfer. [PDF]

J Bacteriol, 2019
Suchland RJ, Carrell SJ, Wang Y, Hybiske K, Kim DB, Dimond ZE, Hefty PS, Rockey DD.   +7 more
europepmc   +1 more source

An Evolutionary Analysis of Lateral Gene Transfer in Thymidylate Synthase Enzymes [PDF]

, 2010
Adi Stern, Itay Mayrose, Osnat Penn, Shaul Shaul, Uri Gophna, Tal Pupko   +5 more
openalex   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

Faculty Opinions recommendation of Deduction of probable events of lateral gene transfer through comparison of phylogenetic trees by recursive consolidation and rearrangement.

, 2005
Jeffrey Lawrence
openalex   +1 more source

Population mixing of Rhizobium leguminosarum bv. viciae nodulating Vicia faba: the role of recombination and lateral gene transfer [PDF]

, 2010
Chang Fu Tian, J. Peter W. Young, En Tao Wang, Samih M. Tamimi, Wen Xin Chen   +4 more
openalex   +1 more source