Results 231 to 240 of about 5,304,033 (262)
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Lateral gene transfer in Salmonella
Microbes and Infection, 2003Comparative genomics and microarrays reveal that the genomes of different Salmonella enterica serovars are distinguished from each other by the presence or absence of hundreds of genes. The distribution of these variable genome regions is often not clonal.
Michael McClelland
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On surrogate methods for detecting lateral gene transfer [PDF]
Surrogate methods for detecting lateral gene transfer are those that do not require inference of phylogenetic trees. Herein I apply four such methods to identify open reading frames (ORFs) in the genome of Escherichia coli K12 that may have arisen by lateral gene transfer.
Mark Ragan
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Lateral Gene Transfer and the Origins of Prokaryotic Groups
Annual Review of Genetics, 2003▪ Abstract Lateral gene transfer (LGT) is now known to be a major force in the evolution of prokaryotic genomes. To date, most analyses have focused on either (a) verifying phylogenies of individual genes thought to have been transferred, or (b) estimating the fraction of individual genomes likely to have been introduced by transfer.
Camilla Lothe Nesbø +2 more
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Detecting Laterally Transferred Genes
2012Methods for identifying alien genes in genomes fall into two general classes. Phylogenetic methods examine the distribution of a gene's homologues among genomes to find those with relationships not consistent with vertical inheritance. These approaches include identifying orphan genes which lack homologues in closely related genomes and genes with ...
Rajeev K, Azad, Jeffrey G, Lawrence
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Lateral and oblique gene transfer
Current Opinion in Genetics & Development, 2001Sequence information from complete genomes, and from multiple loci of strains within species, is transforming the way that we investigate the evolution of bacteria. Such large-scale assessments of bacterial genomes have provided evidence of extensive gene transfer and exchange.
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Lateral Transfer of the lux Gene Cluster
Journal of Biochemistry, 2006The lux operon is an uncommon gene cluster. To find the pathway through which the operon has been transferred, we sequenced the operon and both flanking regions in four typical luminous species. In Vibrio cholerae NCIMB 41, a five-gene cluster, most genes of which were highly similar to orthologues present in Gram-positive bacteria, along with the lux ...
Sabu, Kasai +4 more
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Phylogenetic reconstruction and lateral gene transfer
Trends in Microbiology, 2004Lateral gene transfer (LGT) is often seen as a form of noise, obscuring the phylogenetic signal with which we might hope to reconstruct the evolution of a group of organisms, or indeed the history of all life (the Tree of Life). Such reconstruction might still be possible if the subset of genes conserved among all genomes in a group (or common to all ...
Eric, Bapteste +3 more
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Phage as agents of lateral gene transfer
Current Opinion in Microbiology, 2003When establishing lysogeny, temperate phages integrate their genome as a prophage into the bacterial chromosome. Prophages thus constitute in many bacteria a substantial part of laterally acquired DNA. Some prophages contribute lysogenic conversion genes that are of selective advantage to the bacterial host.
Carlos, Canchaya +4 more
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TOWARDS IDENTIFYING LATERAL GENE TRANSFER EVENTS
Biocomputing 2003, 2002This paper is concerned with evaluating the performance of the model and algorithm in 5 for detecting lateral gene transfers events. Using a Poisson process to describe arrival times of transfer events, a simulation is used to generate "synthetic" gene and species trees.
Louigi Addario-Berry +2 more
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Rates of Lateral Gene Transfer in Prokaryotes: High but Why? [PDF]
Lateral gene transfer is of fundamental importance to the evolution of prokaryote genomes and has important practical consequences, as evidenced by the rapid dissemination of antibiotic resistance and virulence determinants.
Adam Eyre-Walker +2 more
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