Results 91 to 100 of about 4,724,325 (351)

Response of Monopiles Under Lateral Loading By Centrifuge Modeling

نشریه مهندسی دریا, 2016
One of the most common methods to analyze and design monopiles under lateral load is load-displacement curves, particularly the p-y curves, at different locations of the structure.
Hamid Reza Khodaei, Majid Moradi, Abbas Ghalandarzadeh   +2 more
doaj  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Experimental Study on a Laterally Loaded Pile Under Scour Condition Using Particle Image Velocimetry Technology

Journal of Marine Science and Engineering
The monopile foundation is a popular foundation type for offshore wind turbines; due to the harsh marine environment, there are lateral loads applied on the monopile foundation from winds and currents, and scouring also often occurs around the pile ...
Feng Yu, Xiaofeng Yang, Zhaoming Yao, Yaoyao Meng   +3 more
doaj   +1 more source

Performance-based optimization of structures: theory and applications [PDF]

, 2005
Performance-based Optimization of Structures introduces a method to bridge the gap between optimization theory and its practical applications to structural engineering.
Liang, Qing Quan
core  

Similarity Laws for Stressing Heated Wings [PDF]

, 1953
It will be shown that the differential equations for a heated plate with large temperature gradient and for a similar plate at constant temperature can be made the same by a proper modification of the thickness and the loading for the isothermal plate ...
Tsien, H. S.
core   +1 more source

Lateral load bearing capacity modelling of piles in cohesive soils in undrained conditions: An intelligent evolutionary approach

Applied Soft Computing, 2014
The complex behaviour of fine-grained materials in relation with structural elements has received noticeable attention from geotechnical engineers and designers in recent decades.
Alireza Ahangar-Asr, A. Javadi, Ali Johari, Youliang Chen   +3 more
semanticscholar   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

A Software for Optimum Design of Laterally Loaded Bolted Joints

Gazi Üniversitesi Fen Bilimleri Dergisi
Bolted joints, which are one of the detachable joining methods, are used extensively. The reliability of bolted joints is extremely important for the strength and life of the system.
Kadir Sarı, Hakan Dilipak
doaj   +1 more source

Performance of Square Reinforced Concrete Columns Externally Confined by Steel Angle Collars Under Combined Axial and Lateral Load

, 2015
Providing good ductility has become research interest in the area of seismic resistant structures. Particularly in Reinforced Concrete (RC) structure, such ductility is commonly achieved by providing good confinement.
P. Pudjisuryadi, Tavio, P. Suprobo
semanticscholar   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source