Results 41 to 50 of about 4,206,732 (351)

The effect of masonry infill walls on the reinforced concrete frames behavior under lateral load [PDF]

open access: yes, 2020
The reinforced concrete structures with masonry infill walls are widely used to construct buildings in Algeria, as in many parts of the world. According to earthquake analysis, this type of construction can undergo serious damage under seismic load.
LAYADI, Ismail   +3 more
core  

Optimization of force-limiting seismic devices connecting structural subsystems [PDF]

open access: yes, 2016
This paper is focused on the optimum design of an original force-limiting floor anchorage system for the seismic protection of reinforced concrete (RC) dual wall-frame buildings.
Fleischman, Robert B.   +4 more
core   +1 more source

Categorisation of activities of daily living of lower limb amputees during short-term use of a portable kinetic recording system: a preliminary study [PDF]

open access: yes, 2011
The purpose of this preliminary study was to determine the relevance of the categorisation of the load regime data to assess the functional output and usage of the prosthesis of lower limb amputees.
Frossard , Laurent   +4 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Investigation on crossing sheeting distance to steel shear wall and its stiffeners under seismic load [PDF]

open access: yesJournal of Structural and Construction Engineering, 2019
The extensive studies in the field of steel shear walls indicate the initial stiffness, strength, ductility and high energy absorption of this system under cyclic load.
Mahmood Seraji   +2 more
doaj   +1 more source

Lateral Load-Resisting System Using Mass Timber Panel for High-Rise Buildings

open access: yesFrontiers in Built Environment, 2017
As global interest in using engineered wood products in tall buildings intensifies due to the ‘green’ credential of wood, it is expected that more tall wood buildings will be designed and constructed in the coming years.
Zhiyong Chen, Y. Chui
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

An Effective Beam Width Model of Slab in Thick Wall-Thick Slab Joints Subjected to Lateral Forces

open access: yesApplied Sciences, 2022
Thick wall-thick slab structures are a newly-developed type of structural system comprising solely of structural floor slabs and shear walls, the former of which is thicker than that of slabs used in typical reinforced concrete frame structures.
Jiehui Wang, Koichi Kusunoki
doaj   +1 more source

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun   +95 more
wiley   +1 more source

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