Results 101 to 110 of about 1,287,553 (381)

GABAergic neurons regulate lateral ventricular development via transcription factor Pax5 [PDF]

, 2013
Postmortem studies have revealed a downregulation of the transcription factor Pax5 in GABAergic neurons in bipolar disorder, a neurodevelopmental disorder, raising the question whether Pax5 in GABAergic neurons has a role in normal brain development.
Asada, Benes, Bouchard, Ciani, Condie, Edmiston, Estivill-Torrus, Funahashi, Homanics, Horcher, Kempton, Louvi, Ma, Machon, Makiyama, Matsumoto, Meduri, Miller, Muyrers, Novak, Oh, Pfeffer, Rosa, Rowitch, Schwarz, Srinivas, Tamamaki, Tashiro, Tashiro, Thomas, Urbanek, Wojcik, Wurst, Ye, Zygourakis   +34 more
core   +2 more sources

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum. [PDF]

, 2007
Autosomal recessive hereditary spastic paraplegia (ARHSP) with thin corpus callosum (TCC) is a common and clinically distinct form of familial spastic paraplegia that is linked to the SPG11 locus on chromosome 15 in most affected families. We analyzed
AZZEDINE H, BERTINI E, BOUSLAM N, BRICE A., CHARLES P, CHOMILIER J, CONFAVREUX C, COUTINHO P, CRUZ VT, DENORA PS, DURR A, ELLEUCH N, FILLA, ALESSANDRO, FONTAINE B, GRID D, LEGUERN E, LOSSOS A, LOUREIRO, JL, MARTIN E, OUVRARD HERNANDEZ AM, RUBERG M, SANTORELLI FM, STEVANIN G, TAZIR M, TESSA A   +24 more
core  

Uniplanar nystagmus associated with perceptual and cognitive visual dysfunction due to presumed focal ischemic occipital cortical atrophy: a missed diagnosis and new observation [PDF]

, 2012
Uniplanar nystagmus has been described in relation to pathology of the brain stem, retina, optic nerve, sensory visual deprivation, periventricular leucomalacia, and drug toxicity.
Dorris, Liam, Dutton, Gordon N., Philip, Swetha Sara   +2 more
core   +3 more sources

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

Advanced Science, EarlyView.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang, Tinghong Liu, Zhirong Wei, Jinshan Xu, Jiayi Han, Jiaqi Wang, Feng Zhai, Yiran Tian, Shuli Liang   +8 more
wiley   +1 more source

Clinical Observation of a Child with Astrocytoma

Zdorovʹe Rebenka, 2013
The article deals with the result of clinical observation of a child with astrocytoma and lesion of subependymal zones of lateral ventricles of the brain and gray tuber.
T.V. Sirenko, O.V. Piontkovskaya, A.A. Khotsenko, O.N. Plakhotnaya, A.V. Postnikov, T.A. Khalturina   +5 more
doaj   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Neuroradiological diagnosis meningiomas among the primary tumors of lateral ventricles

Ендоваскулярна нейрорентгенохірургія, 2018
Objective – to determine the main of neuroimaging characteristics meningiomas among primary tumors of the lateral ventricles. Materials and methods. The work is based on the analysis of a retrospective and prospective multicentric study.
M.E. Polischuk, M.K. Mehrzi, A.G. Sirko, O.M. Goncharuk, O.M. Voznyak, M.S. Kvasha, V.V. Kondratyuk, O.L. Mehrzi-Feduna   +7 more
doaj   +1 more source

Hemangioblastoma of the lateral ventricle

JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA, 2018
Introduction: Hemangioblastomas are capillary-rich benigntumors mainly found in the infratentorial compartment. When at the supratentorial space, they are rarely located at the lateral ventricle. We report on a case of a 25 years-old female patient treated at our institution.
Carlos Augusto Ferreira Lobão, Albedy Moreira Bastos, Leonidas Braga Dias Junior   +2 more
openaire   +2 more sources

Baseline and Longitudinal Changes in Lateral Ventricle Volume Predict Cognitive Decline [PDF]

, 2023
Gengsheng Chen, Brian A. Gordon, Qīng Wáng, Suzanne E. Schindler, Nicole S. McKay, Jingxia Liu, Nelly Joseph‐Mathurin, Sarah Keefe, Andrew J. Aschenbrenner, Parinaz Massoumzadeh, John C. Morris, Tammie L.S. Benzinger   +11 more
openalex   +1 more source