Results 31 to 40 of about 5,141,751 (283)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Schneider Membrane Elevation in Presence of Sinus Septa: Anatomic Features and Surgical Management

International Journal of Dentistry, 2012
Maxillary sinus floor elevation via a lateral approach is a predictable technique to increase bone volume of the edentulous posterior maxilla and consequently for dental implants placement.
Mario Beretta, Marco Cicciù, Ennio Bramanti, Carlo Maiorana   +3 more
doaj   +1 more source

Save the Greater Trochanter: A Novel Modification to the Extended Trochanteric Osteotomy

Arthroplasty Today, 2022
The extended trochanteric osteotomy is the workhorse for removal of well-fixed femoral stems during total hip revision arthroplasty. Despite its reliable performance in exposing the implants for removal and accessing the femoral canal, significant ...
Eric B. Smith, MD
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Excision and Patch Grafting of a Lateral Peyronie's Plaque—Utilizing a Longitudinal “Window” Approach

Sexual Medicine, 2015
Introduction: Peyronie's disease (PD) is a debilitating disorder in which collagen deposition, fibrosis, and plaques in the tunica albuginea result in penile curvature, shortening, and pain.
Kathy Lue, BS, Justin B. Emtage, MD, Daniel R. Martinez, MD, Christopher Yang, MD, Rafael Carrion, MD   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Expanding window fountain codes for unequal error protection [PDF]

, 2007
A novel approach to provide unequal error protection (UEP) using rateless codes over erasure channels, named Expanding Window Fountain (EWF) codes, is developed and discussed.
Vukobratovic, D, Senk, Vojin, Dejan Vukobratovic, Piechocki, RJ, Sejdinovic, D, Vukobratovic, Dejan, Dino Sejdinovic, Angela Doufexi, Doufexi, A, Vojin Senk, Robert J. Piechocki, Senk, V, Sejdinović D., Piechocki R., Doufexi A., R. Piechocki, A. Doufexi, D. Sejdinovic, D. Vukobratovic, V. Senk   +19 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Assessment of 3D Lumbosacral Vascular Anatomy for OLIF51 by Non-Enhanced MRI and CT Medical Image Fusion Technique

Diagnostics, 2021
Study design: Prospective study. Objective: Medical image fusion can provide information from multiple modalities in a single image. The present study aimed to determine whether three-dimensional (3D) lumbosacral vascular anatomy could be adequately ...
Masakazu Nagamatsu, Sameer Ruparel, Masato Tanaka, Yoshihiro Fujiwara, Koji Uotani, Shinya Arataki, Taro Yamauchi, Yoshiyuki Takeshita, Rika Takamoto, Masato Tanaka, Shinsuke Moriue   +10 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source