Results 31 to 40 of about 125,836,251 (258)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The Impact of EU Accession on the Development of Administrative Capacities in the States in Central and Eastern Europe. Similar Developments in Russia? [PDF]
Romanian Journal of European Affairs, 2006 The developments of the civil service and administrative reform in Central and Easter European countries and in Russia are more or less similar. For the Central and Eastern European countries explicitly EU Membership is mentioned as an incentive for ...
Alfred E. Kellermann
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Precautionary in International Law: A Customary Principle or a General Principle of Law? [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2018 It took humankind a long time to realize its inability to understand different aspects of environmental risks and find that it would bear irreversible damage if such a risk occurs.
Abbasali KadKhodaei, Asma Salari
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
EMU in the Case Law of the Union Courts: A General Overview and Some Observations
European Papers, 2022 (Series Information) European Papers - A Journal on Law and Integration, 2021 6(3), 1397-1414 | Article | (Table of Contents) I. Introduction. - II. Four main categories of CJEU cases. - II.1. EMU and the euro and debt crisis in general. - II.2. Problems
Allan Rosas
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Confederation and federation in the general theory of law and state and in positive law [PDF]
Zbornik Radova Pravnog Fakulteta u Nišu, 2016 Scientific interest in issues concerning federalism, which implies determining the difference between a confederation (a union of confederal states) and a federation (a federal state comprising federal entities) seems to have disappeared after the ...
Petrović Milan
doaj +1 more source
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source