Results 111 to 120 of about 128,206 (299)
Drawing the Line: An Exploration of How Lay People Construct Child Neglect
This thesis uses a Foucauldian approach to explore how lay people construct child neglect in England. The concept of child neglect developed after the Industrial Revolution in conjunction with the construction of ‘normal’ childhood.
Williams, Sasha
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Lire Dante aujourd’hui. Un parcours entre France et Italie (deuxième partie)
, 2022 Summary /Read Dante today.A journey between France and Italy /under the supervision of Cécile Le Lay and Guido Castelnuovo /Cécile LE LAY et Guido CASTELNUOVOIntroduction /1. Dante: his culture, his readings, his interpretations /Guido CASTELNUOVO“O poca
Castelnuovo, Guido, Le Lay, Cécile
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Silver Saplings Adventures for Older People: a qualitative review and evaluation of intended positive interventional change and wellbeing effects for participants of the programme: lay summary document. [PDF]
This is a lay summary of the qualitative review and evaluation of the Silver Saplings Adventures programme.
Adams, Nick +3 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Parliamentary Procedure: Lay on the Table
EDIS, 2013 The motion to Lay on the Table is used to temporarily delay action on a pending question while something else of immediate urgency needs consideration, or when another item of business needs to be addressed before consideration of the pending question ...
James E. Dyer
doaj +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source