Results 121 to 130 of about 42,248,778 (304)

Layer-by-layer analyses of choroidal structures of treatment eyes and the fellow eyes before and after half-dose PDT.

, 2016
Layer-by-layer analyses of choroidal structures of treatment eyes and the fellow eyes before and after half-dose PDT.
Yoshinori Mitamura (361411), Junya Mori (3124161), Taiji Sakamoto (104961), Kentaro Semba (138862), Mariko Egawa (3124158), Kei Akaiwa (3124155), Shozo Sonoda (104941), Takamasa Kinoshita (1675516), Terumi Mori (2946924)   +8 more
core   +1 more source

Fast and safe fabrication of a free-standing chitosan/alginate nanomembrane to promote stem cell delivery and wound healing

International Journal of Nanomedicine, 2016
Yi Kong,1,2,* Rui Xu,1,* Mohammad Ali Darabi,2 Wen Zhong,3 Gaoxing Luo,1 Malcolm MQ Xing,1,2 Jun Wu1 1Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns, and Combined Injury, Chongqing Key Laboratory for Diseases ...
Kong Y, Xu R, Darabi MA, Zhong W, Luo G, Xing MMQ, Wu J   +6 more
doaj  

Facile universal strategy of presenting multifunctional short peptides for customizing desired surfaces

Journal of Nanobiotechnology
Interfacial properties determine biomaterial performances, such as cell adhesion, signal exchange, and biomineralization, which affect the tissue repair cycle and efficiency of clinical applications. Peptides, as short protein sequences that have defined
Ruofei Lu, Bingyang Zhao, Kaiyuan Huo, Hao Liu, Yang Wang, Xingjie Zan, Siwang Hu   +6 more
doaj   +1 more source

How GPT learns layer by layer

CoRR
Large Language Models (LLMs) excel at tasks like language processing, strategy games, and reasoning but struggle to build generalizable internal representations essential for adaptive decision-making in agents. For agents to effectively navigate complex environments, they must construct reliable world models.
Jason Du, Kelly Hong, Alishba Imran, Erfan Jahanparast, Mehdi Khfifi, Kaichun Qiao   +5 more
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Control of shock-induced boundary layer separation at supersonic speeds

, 2007
PhDThe results of a systematic experimental investigation into the effects that Sub- Boundary Layer Vortex Generators (SBVGs) have on reducing normal shock-induced turbulent boundary layer separation are presented.
Cohen, Giel S, Cohen, Giel S.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Layers and layer interfaces in wireless networks

2009 IEEE International Conference on Acoustics, Speech and Signal Processing, 2009
This paper proposes an optimal architecture for wireless networks based on layers and layer interfaces. In the presence of fading the architecture is shown to be optimal. The result follows from a subgradient descent algorithm on the dual function of a generic wireless networking optimization problem.
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source