Results 111 to 120 of about 58,089,599 (262)

Nanostructured Biomaterials with Controlled Properties Synthesis and Characterization

Nanoscale Research Letters, 2009
Magnetic nanoparticles were obtained using an adjusted Massart method and were covered in a layer-by-layer technique with hydrogel-type biocompatible shells, from chitosan and hyaluronic acid.
Petcu C, Somoghi Raluca, Teodor Eugenia, Liţescu SimonaCarmen, Mihalache Mihaela   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Fast and safe fabrication of a free-standing chitosan/alginate nanomembrane to promote stem cell delivery and wound healing

International Journal of Nanomedicine, 2016
Yi Kong,1,2,* Rui Xu,1,* Mohammad Ali Darabi,2 Wen Zhong,3 Gaoxing Luo,1 Malcolm MQ Xing,1,2 Jun Wu1 1Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns, and Combined Injury, Chongqing Key Laboratory for Diseases ...
Kong Y, Xu R, Darabi MA, Zhong W, Luo G, Xing MMQ, Wu J   +6 more
doaj  

Facile universal strategy of presenting multifunctional short peptides for customizing desired surfaces

Journal of Nanobiotechnology
Interfacial properties determine biomaterial performances, such as cell adhesion, signal exchange, and biomineralization, which affect the tissue repair cycle and efficiency of clinical applications. Peptides, as short protein sequences that have defined
Ruofei Lu, Bingyang Zhao, Kaiyuan Huo, Hao Liu, Yang Wang, Xingjie Zan, Siwang Hu   +6 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Layer-by-Layer Assembly of Thin Film Zener Diodes from Conducting Polymers and CdSe Nanoparticles

, 2016
Ultrathin films have been prepared by self-assembling trioctylphosphine oxide, TOPO, capped n-type 20−40 Å diameter CdSe nanoparticles and 1,6-hexadecanethiol, HDT, onto p-doped semiconducting polymers, chemically deposited poly(3-methylthiophene), PMeT (
Thierry Cassagneau (2986374), Thomas E. Mallouk (1275909), Janos H. Fendler (2699869)   +2 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Layer-by-Layer Grown Electrodes Composed of Cationic Fe₃O₄ Nanoparticles and Graphene Oxide Nanosheets for Electrochemical Energy Storage Devices

, 2019
Ultrathin electrodes composed of layer-by-layer assembled (3-aminopropyl)­trimethoxysilane functionalized iron oxide nanoparticles and graphene oxide nanosheets were prepared by a simple and low-cost dip coating method without using any binders or ...
Emre Erdem (2306434), F. Eylul Sarac Oztuna (6297326), Havva Yagci Acar (2301196), Ugur Unal (2483383), Ozlem Unal (6297329)   +4 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source