Results 71 to 80 of about 57,179,822 (251)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Layer-by-layer assembly of antibacterial coating on interbonded 3D fibrous scaffolds and its cytocompatibility assessment

open access: yes, 2012
Layer-by-layer assembly of antibacterial coating on interbonded 3D fibrous scaffolds and its cytocompatibility ...
Yan Zhao (13100625)   +6 more
core  

Layer-by-Layer Assembly Strategy for Reinforcing the Mechanical Strength of an Ionogel Electrolyte without Affecting Ionic Conductivity

open access: yes, 2019
The simultaneous boosting of the ionic conductivity and the mechanical strength of an ionogel electrolyte is hindered by its entrapped electrolyte. Herein, we report a promising strategy to boost the mechanical strength of an ionogel by coating it with ...
Bishnu P. Thapaliya (8104181)   +2 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Filmes poliméricos ultrafinos produzidos pela técnica de automontagem: preparação, propriedades e aplicações

open access: yesQuímica Nova, 2001
The self-assembly technique is a powerful tool to fabricate ultrathin films from organic compounds aiming at technological applications in molecular electronics.
Paterno Leonardo Giordano   +2 more
doaj  

Nanoshell Fabrication Techniques for Probiotic Encapsulation: A Comprehensive Review

open access: yeseFood
Probiotics, beneficial microorganisms, confer numerous health benefits when administered. However, their efficacy is hindered by harsh gut conditions, including acidity, bile acids, and enzymatic degradation.
Tuba Mustafa   +12 more
doaj   +1 more source

Surface Modification of Dental Titanium Implant by Layer-by-Layer Electrostatic Self-Assembly

open access: yesFrontiers in Physiology, 2017
In vivo implants that are composed of titanium and titanium alloys as raw materials are widely used in the fields of biology and medicine. In the field of dental medicine, titanium is considered to be an ideal dental implant material.
Quan Shi   +3 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Classification of hyper-variable Corynebacterium glutamicum surface-layer proteins by sequence analyses and atomic force microscopy [PDF]

open access: yes, 2004
Hansmeier N, Bartels FW, Ros R, et al. Classification of hyper-variable Corynebacterium glutamicum surface-layer proteins by sequence analyses and atomic force microscopy. J Biotechnol.
Hansmeier, Nicole   +6 more
core   +1 more source

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