Results 71 to 80 of about 642,291 (297)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Layer-By-Layer Assembly of Complex Membranes [PDF]
Biophysical Journal, 2013 Reconstituting complex biological macromolecular and supramolecular structure and function from simple chemical starting materials is the central goal of bottom-up synthetic biology. Phospholipid bilayer membranes, which represent a critically important class of such structures, are central to the study of signal transduction pathways, membrane ...
Matosevic, Sandro, Paegel, Brian
openaire +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Layer-by-layer functionalisation of composite membranes for bone in vivo regeneration
, 2017 The data represent the physico-chemical and biological characterisation of electrospun membranes functionalised by Layer-by-layer assembly.
J Callaghan (7836350) +2 more
core +1 more source
Layer-by-Layer Assembly of CeO2 Nanoparticle/Bovine Serum Albumin Films for Bone Regeneration
, 2023 As a critical factor in bone regeneration, oxidative stress affects the effectiveness of implantation seriously. Construction of bioactive coatings with ideal antioxidative and osteogenic activities is essential for the repair of bone injury.
Shuoshuo Yang (6872285) +5 more
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Engineering in Life Sciences, 2021 Pulping and papermaking generate large amounts of waste in the form of lignosulfonates which have limited valorized applications so far. Herein, we report a novel lignosulfonate‐based nanofiltration membrane, prepared by using polyethylenimine (PEI) and ...
Wangqu Liu +6 more
doaj +1 more source
, 2019 The growing demand for compact energy storage devices may be met through the use of thin-film microbatteries, which generally rely on charge storage in thin or conformal layers.
Paraskevi Flouda (8115392) +23 more
core +1 more source
, 2022 Airborne pathogens, such as the world-spreading severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), cause global epidemics via transmission through the respiratory pathway.
Ming Ke (3796756) +10 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source