Results 71 to 80 of about 3,044,337 (312)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Antibiotic residues in broiler and layer meat in Chittagong district of Bangladesh [PDF]
Veterinary World, 2014 Aim: The present study was described thin layer chromatography (TLC) and ultra-high performance liquid chromatography (UHPLC) method for the detection of antibacterial substances in poultry muscle (breast and thigh), kidney, and liver.
Sarmina Sattar +6 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Structure of the Turbulent Boundary Layer under Static and Dynamic Impulsive Roughness Perturbation [PDF]
, 2013 The zero-pressure gradient turbulent boundary layer at Reynolds numbers (based on momentum thickness) ranging from 2700--4100 was perturbed using an impulsively short patch of two-dimensional, spanwise roughness elements.
Jacobi, Ian
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A numerical model study of the stratocumulus-topped marine boundary layer [PDF]
, 1999 A one-dimensional model with second order turbulence closure has been developed and used to investigate processes in the cloud-topped marine atmospheric boundary layer.
Kent, E.C.
core
Composite hodographs and inertial oscillations in the nocturnal boundary layer
, 2011 In this work the dynamic behaviour of the wind in the nocturnal boundary layer is studied, with a particular focus on systematic behaviour of the near-surface wind.
P. Baas +15 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Layer by layer, spin by spin [PDF]
Science AdvancesThere comes a time in every academic life when the level of responsibility becomes terrifying. In my five years at Science Advances, first as an associate and then as a deputy editor, there was always a benevolent superpower at the top – it had never intervened but its existence created a peace of mind.
openaire +2 more sources
Temporal and spatial variation in active layer depth in the McMurdo Sound Region, Antarctica
, 2010 A soil climate monitoring network, consisting of seven automated weather stations, was established between 1999 and 2003, ranging from Minna Bluff to Granite Harbour and from near sea level to about 1700m on the edge of the polar plateau.
Seybold, Cathy A. +3 more
core +1 more source