Results 111 to 120 of about 134,743 (297)

Uniaxial Compression Test and Numerical Study on the Mechanical Mechanism of Crack Exhibition and Propagation in Layered Rocks

Applied Sciences
Layered rocks are widely distributed in mining and underground engineering. The evolution processes, such as crack initiation, development and penetration, inevitably occur due to stress changes.
Zhengnan Zhang, Xiangxin Liu, Bin Gong, Zhengzhao Liang, Xianxian Liu, Xun You   +5 more
doaj   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

A review of computational approaches for simulating fracturing mechanisms in layered rock formations

International Journal of Coal Science & Technology
With the increasing availability and sophistication of computer hardware and software, computational modelling has become a cornerstone in the understanding of geomaterials mechanical behaviours over recent decades.
Hongtao Li, Jimeng Feng, Dong Su, Xiangsheng Chen, Xingsen Guo   +4 more
doaj   +1 more source

Failure behaviors of anisotropic shale with a circular cavity subjected to uniaxial compression

Journal of Rock Mechanics and Geotechnical Engineering
Layered rock formations are frequently encountered during the excavation of underground structures. The stability of such structures is influenced not only by the stress concentration caused by the cavities in the strata but also by the anisotropy of the
Xianhui Feng, Huilin Liu, Peitao Wang, Shichao Zhang, Quanqi Zhu, Chun'an Tang, Yaxing Leng   +6 more
doaj   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Crack growth properties and AE phenomena in notched hard/soft layered rock under punch shear test; experimental test and numerical simulation

Results in Engineering
Facing layered rocks is common in various mining geotechnical and tunnel engineering projects. These layers vary in thickness and are separated by bedding planes, which can either be cemented together or distinct from each other.
Seyed Davoud Mohammadi, Rahim Mortezaei, Vahab Sarfarazi, Arsham Moayedi Far   +3 more
doaj   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

Research on the influence of rock fracture toughness of layered formations on the hydraulic fracture propagation at the initial stage

Geohazard Mechanics
Deep underground rocks exhibit significant layered heterogeneity due to geological evolution and sedimentation. Rock fracture toughness, as one of the important indicators of hydraulic crack propagation, also exhibits heterogeneous distribution. In order
Kairui Li, Chengzhi Qi, Mingyang Wang, Jie Li, Haoxiang Chen   +4 more
doaj   +1 more source