Results 21 to 30 of about 9,555 (264)
Bedding Plane Effects on Mechanical Behavior of Surrounding Rock in Mountain Tunneling
Shock and Vibration, 2021 The layered rock showed the characteristics in Mountain tunnel, Yunnan. A series of uniaxial compression tests and variable angle shear tests were carried out, and the aim was to investigate the effect of the bedding on its mechanical parameters and ...
Shuang You, Jincui Sun, Hongtao Wang
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Underground Space, 2023 Due to complex geological formations, lateral damage often occurs during excavation in mountainous layered soft rock double-track tunnels. This paper discusses the stresses and the damage characteristics of the surrounding rock under overload in a ...
Qiru Sui +6 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
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Energy Science & EngineeringCoal‐measure strata is a typical layered structure, a better understanding of the bearing characteristics of fully grouted bolts in layered rock mass is of great significance for roadway support.
Yunlou Du +4 more
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Tunnel surrounding rock plastic zone in the layered rock mass with the elastoplastic theory
Shuiwen dizhi gongcheng dizhiExisting theoretical studies on the plastic zone of tunnel surrounding rock mainly focus on the circular tunnel in the isotropic rock mass, with limited attention paid to layered rock mass.
Shudong ZHOU +4 more
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Dike propagation through layered rocks [PDF]
Journal of Geophysical Research: Solid Earth, 2009 Dike penetration through a succession of upper crustal layers with different densities is studied with a new numerical code. For an individual layer to significantly affect dike ascent, its thickness must be of order 1 when scaled to the characteristic length‐scale for the inflated nose region that develops below the dike tip.
Taisne, B., Jaupart, C.
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
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Research on Damage Evolution Mechanism of Layered Rock Mass under Blasting Load
BuildingsRock mass consists of many discontinuities, such as faults, joints, etc., and layered joints are a common kind of rock mass structure. The joints affect the stress wave propagation, and blasting is an economical and efficient rock fragmentation method ...
Lixiang Xie +5 more
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Open Geosciences, 2023 Layered rock slopes are the most widely distributed slopes with the simplest structure. The classification of layered rock slopes is the basis for correctly analyzing their deformation and failure mechanisms, evaluating their stability, and adopting ...
Shang Hao +5 more
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