Results 31 to 40 of about 902 (216)

Study on deformation of layered rock tunnel based on material point method [PDF]

open access: yesArchives of Civil Engineering
The stability problems of layered rock mass are frequently encountered in tunnel and underground engineering. Affected by bedding plane, the mechanical properties of surrounding rock show obvious anisotropy, which makes its failure characteristics more ...
Jingjie Pang   +6 more
doaj   +1 more source

Kernel broken smooth particle hydrodynamics method for crack propagation simulation applied in layered rock cells and tunnels

open access: yesUnderground Space, 2023
Understanding the cracking process of layered tunnels requires a high-fidelity method. Improved smooth particle hydrodynamics (SPH), termed kernel broken SPH (KBSPH), was implemented to simulate the crack propagation and deformation of layered rock cells
Chengzhi Xia   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Effect of layering characteristics on compressive mechanical properties and damage mechanisms of rocks: Experiments and models.

open access: yesPLoS ONE
The investigation of layered rock mechanical properties is important for rock stability analysis. To examine the effects of layer inclination angle (LIA) and layer thickness (LT) on the compressive mechanical properties and damage mechanism of layered ...
Chong Chen   +5 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Blastability Classification of Fractured Rock Mass Based on Weighted Clustering Analysis

open access: yesChemical Engineering Transactions, 2017
This paper classifies the blastability of fractured rock mass based on the solid coefficient, rock impedance, unit explosive consumption and mean fracture spacing. Specifically, an evaluation model was established according to the principle of clustering
Tiejun Tao   +4 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Multimodal Data‐Driven Microstructure Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang   +4 more
wiley   +1 more source

Deformation Characteristics and Response Factors of Rock Bolt Body in Roadway with Layered Composite Roof

open access: yesApplied Sciences
Layered composite roofs are characterized by developed bedding fissures, resulting in severe deformation and damage of rock bolts at the top of the roadway, as well as a poor roadway support effect.
Ziyue Wang, Shangxin Fang, Cun Zhang
doaj   +1 more source

Experimental Study on Deformation Law of Rectangular Roadway in Horizontal Layered Rock Mass

open access: yesAdvances in Materials Science and Engineering, 2022
In order to analyze the characteristics and mechanism of roadway deformation caused by high stress in horizontal strata, a physical model with rectangular roadway was designed.
Dinggui Hou   +2 more
doaj   +1 more source

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