Results 91 to 100 of about 5,863 (268)

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Synthetic Rock Analogue for Permeability Studies of Rock Salt with Mudstone

Applied Sciences, 2017
Knowledge about the permeability of surrounding rock (salt rock and mudstone interlayer) is an important topic, which acts as a key parameter to characterize the tightness of gas storage.
Hongwu Yin, Hongling Ma, Xiangsheng Chen, Xilin Shi, Chunhe Yang, Maurice B. Dusseault, Yuhao Zhang   +6 more
doaj   +1 more source

Faster and Durable: A Cell‐to‐System Validation of a Low‐Degradation Fast‐Charge Protocol for Li‐Ion Batteries

Advanced Science, EarlyView.
A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni, Francesco Giuseppe Quilici, Davide Cademartori, Claudio Scarpelli, Uways Nurulain Mithoowani, Federica Barontini, Alessandro Ruvio, Monica Puccini, Giovanni Lutzemberger, Maria Paola Carpanese, Antonio Bertei   +10 more
wiley   +1 more source

Trifunctional Kinetic Regulation Enables Low‐Defect Solution Grown Single Crystals for X‐Ray Detection

Advanced Science, EarlyView.
This work presents a molecular‐level kinetic regulation strategy employing iodoacetic acid (IAA) to simultaneously suppress point defects and solvent inclusion in solution‐grown Cs4PbI6 single crystals. The obtained crystals demonstrate significantly enhanced charge transport properties, enabling X‐ray detectors with high sensitivity, low noise, and ...
Hui Zhang, Zihan Wang, Zhenyu Wang, Changmao Wan, Zheng Liang, Huifen Xu, Yuanbo Ma, Yupeng Liu, Xu Pan, Jiajiu Ye   +9 more
wiley   +1 more source

Uniaxial Compression Test and Numerical Study on the Mechanical Mechanism of Crack Exhibition and Propagation in Layered Rocks

Applied Sciences
Layered rocks are widely distributed in mining and underground engineering. The evolution processes, such as crack initiation, development and penetration, inevitably occur due to stress changes.
Zhengnan Zhang, Xiangxin Liu, Bin Gong, Zhengzhao Liang, Xianxian Liu, Xun You   +5 more
doaj   +1 more source

Sequence of infilling events in Gale crater, Mars: Results from morphology, stratigraphy, and mineralogy

, 2013
Gale Crater is filled by sedimentary deposits including a mound of layered deposits, Aeolis Mons. Using orbital data, we mapped the crater infillings and measured their geometry to determine their origin.
Fueten, F., Hauber, E., Rossi, A.P., Jaumann, R., Frank Fueten, Laetitia Le Deit, Ernst Hauber, Pondrelli, M., Ralf Jaumann, Rossi, A.,, Rossi, A., P, Pondrelli, M, Le Deit, L., Angelo Pio Rossi, Monica Pondrelli, Le Deit, Laetitia   +15 more
core   +1 more source

Deformation and Stability Characteristics of Layered Rock Slope Affected by Rainfall Based on Anisotropy of Strength and Hydraulic Conductivity

, 2020
The strength and hydraulic conductivity anisotropy of rock slopes have a great impact on the slope stability. This study took a layered rock slope in Pulang, Southwestern China as a case study. The strength conversion equations of the seriously weathered
Guangyin Lu, Ziqiang Zhu, Chengzhi Xia, Liang Zhang, Jie Dong, Shuai Luo, Lianrong Wu   +6 more
core   +1 more source

Mechanically Adaptive Polyimide Interfaces for Stable High‐Voltage NCM–Sulfide All‐Solid‐State Batteries

Advanced Science, EarlyView.
A mechanically adaptive polyimide interface dynamically stabilizes single‐crystal cathodes in sulfide all‐solid‐state batteries. By integrating robust chemical coordination with viscoelastic compliance, this smart coating suppresses parasitic reactions and accommodates cyclic volume expansion.
Jiatao Wu, Wenjin Li, Rui Wang, Peng Wang, Kaiyuan Deng, Chengshuai Chang, Chuan Xie, Lei Yao, Guangliang Gary Liu   +8 more
wiley   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

STRESSES AROUND A TUNNEL PASSING THROUGH A LAYERED ROCK MASS

ABSTRACT: The article addresses the issue of determining the stresses around a tunnel with a circular cross-section. It passes through several rock layers. The boundary planes between the layers are arbitrarily inclined relative to the tunnel axis. Furthermore, the planes are parallel to the horizontal axis of the tunnel crosssection.The specified ...
Trifonova-Genova, Violeta, Tonkova, Gergana   +1 more
openaire   +2 more sources