Results 111 to 120 of about 4,217,928 (269)
Elastic moduli for fractured rock mass
, 2013 The presence of joint discontinuities has long been recognized as an important factor influencing the mechanical behavior of rock masses. This paper proposes a stress-strain model for an assemblage of intact rock blocks separated by joint planes.
Huang, T. H.; Chang, C. S.; Yang, Z. Y.
core +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
A new empirical approach for prediction of rock mass strength based on a strength reducing curve zone instead of unique strength reducing curve [PDF]
, 2010 ISRM International Symposium - 6th Asian Rock Mechanics Symposium: Advances in Rock Engineering, ARMS 2010 -- 23 October 2010 through 27 October 2010 -- New Delhi -- 139012As is well known from rock mechanics literature, the mechanical parameters of a ...
Sonmez, Harun +4 more
core +1 more source
Advanced Science, EarlyView.Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin +7 more
wiley +1 more source
Advanced Science, EarlyView.High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling +18 more
wiley +1 more source
, 2016 The Coal Mine Roof Rating (CMRR) classification system has been applied in a number of coal mines worldwide including Australia. This system is very useful for mine planners as it provides reliable and repeatable information about the roof properties ...
Guardado, M., Taheri, A.
core
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Advanced Science, EarlyView.Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann +7 more
wiley +1 more source
Journal of Rock Mechanics and Geotechnical EngineeringThe rock mass integrity index (Kv) is a widely used parameter for characterizing rock mass integrity. Kv is defined as the square of the ratio of the P-wave velocity of a rock mass to that of intact rock. Usually, due to the presence of structural planes
Yongbin Liu +5 more
doaj +1 more source
Advanced Science, EarlyView.High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang +11 more
wiley +1 more source