Results 51 to 60 of about 5,371 (247)

Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption

open access: yesAdvanced Functional Materials, EarlyView.
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy   +7 more
wiley   +1 more source

Chitin‐Derived Carbon‐Metal Functional Materials

open access: yesAdvanced Functional Materials, EarlyView.
Functional carbon materials are synthesized from combination of biopolymer (chitin) and iron precursors. The resultant material exhibits superior surface area and adsorptive properties compared to carbon materials synthesized directly from pure chitin.
Herry Fang   +7 more
wiley   +1 more source

Effect of layered joints on rockburst in deep tunnels

open access: yesInternational Journal of Coal Science & Technology, 2022
The existence of joints in the surrounding rock mass has a considerable effect on tunnel rockbursts. Herein, we studied the effect of layered joints with different inclination angles and spacings on rockburst in deep tunnels and investigated the failure ...
Mingming He   +3 more
doaj   +1 more source

Nanofiber‐Supported Decellularized Matrix Membrane Creates a Biomimetic Biochemical and Biophysical Niche for Intestinal Organoid Epithelium

open access: yesAdvanced Healthcare Materials, EarlyView.
A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn   +7 more
wiley   +1 more source

Study on deformation of layered rock tunnel based on material point method [PDF]

open access: yesArchives of Civil Engineering
The stability problems of layered rock mass are frequently encountered in tunnel and underground engineering. Affected by bedding plane, the mechanical properties of surrounding rock show obvious anisotropy, which makes its failure characteristics more ...
Jingjie Pang   +6 more
doaj   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Failure behaviors of anisotropic shale with a circular cavity subjected to uniaxial compression

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
Layered rock formations are frequently encountered during the excavation of underground structures. The stability of such structures is influenced not only by the stress concentration caused by the cavities in the strata but also by the anisotropy of the
Xianhui Feng   +6 more
doaj   +1 more source

Earth pressure on a retaining structure in layered and jointed rock masses

open access: yesKSCE Journal of Civil Engineering, 2017
This work looked into the earth pressure induced on retaining walls in different rock layer formations and joint conditions. Based on the simulation of a large-scale expermental test, extended numerical tests were carried out focusing on the effect of various rock layer formations on earth pressure characteristics.
Moorak Son, Solomon Adedokun
openaire   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan   +7 more
wiley   +1 more source

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