Results 111 to 120 of about 52,889 (308)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2013 These documents have been reviewed by Safe AssignmentDESIGN WITH layering. The layering creates spaces that are safe, disconnected and protected from the outside.
Schultz, Samantha
core
Equivolumetric layering for mesh surfaces
, 2018 <p>First release of code for equivolumetric layering of mesh surfaces using CIVET or FreeSurfer</p ...
Casey Paquola (6714824) +9 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Multilist layering: Complexity and applications
, 1995 A natural combinatorial generalization of the convex layer problem, termed multilist layering, is introduced. It is observed to be P-complete in the general case.
Lingas, Andrzej +2 more
core +1 more source
Layering methodological tools to represent classroom collectivity [PDF]
, 2022 Our research is guided by the question: “How might we observe, document, display, and analyze data from a collective systems perspective?” In this research forum, we share new research tools for studying mathematics classrooms, highlight opportunities ...
Simmt, Elaine +9 more
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Study on the layering of the zhongzhou ancient city based on Historical map translation
Journal of Asian Architecture and Building EngineeringChina has witnessed rapid urbanization since the 1980s, accompanied by increasingly prominent contradictions between protecting and renewing historical cities.
Xiaoxia Lang, Guanyu Wei, Gab-Soo Han
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source