Results 111 to 120 of about 95,587 (223)

A Network‐Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology

JOR SPINE, Volume 9, Issue 2, June 2026.
A literature‐based signaling network capturing the most relevant pathways in human nucleus pulposus cells was first constructed from curated biological evidence. The network was then translated into a system of ordinary differential equations to derive steady‐state solutions and define median baseline activity levels.
Sofia Tseranidou, Zerihun G. Workineh, Maria Segarra‐Queralt, Francis Kiptengwer Chemorion, Paola Bermudez‐Lekerika, Exarchos Kanelis, Katherine B. Crump, Benjamin Gantenbein, Leonidas G. Alexopoulos, Christine L. Le Maitre, Janet Piñero, Jérôme Noailly   +11 more
wiley   +1 more source

Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age‐, Sex‐, and BMI‐Matched Pilot Study

JOR SPINE, Volume 9, Issue 2, June 2026.
Chronic low back pain in patients without advanced disc degeneration is associated with gut microbiome dysbiosis, marked by reduced microbial diversity and altered bacterial composition. These findings support a gut–disk axis in which impaired gut barrier integrity and systemic inflammation may contribute to disc inflammation, nociceptive fiber ...
Stone Sima, Thomas Jeffries, Alisha Sial, Suhani Sharma, Neha Chopra, Fan Zhang, Georgina Hold, Wentian Li, Ji Tu, Victor Chen, Ashish Diwan   +10 more
wiley   +1 more source

Mast Cells and Their Related Gene HK-1 are Closely Associated with Discogenic Low Back Pain: A Bioinformatics and Clinical Sample Study

Journal of Pain Research
Shouyu He,1,* Xiaowen Liu,2,* Shenchang Luo,1 Haidong Li,1 Jikang Min,1 Qian Shi3 1Department of Spine Surgery, First Affiliated Hospital, The First People’s Hospital of Huzhou, Huzhou University, Huzhou, 313000, People’s Republic of China ...
He S, Liu X, Luo S, Li H, Min J, Shi Q
doaj  

Transient formation of supramolecular complexes between hyaluronan and oligopeptides at submicromolar concentration

Communications Chemistry
Charged polymer interactions govern biological and technological processes by altering the structure and dynamics of surrounding water. Studying these interactions across a broad concentration range is challenging, particularly at submicromolar levels ...
Miguel Riopedre-Fernandez, Bingxin Chu, Anna Kuffel, Arianna Marchioro, Denys Biriukov, Hector Martinez-Seara   +5 more
doaj   +1 more source

Survival outcomes and prognostic factors of gastric carcinoma with neuroendocrine differentiation

International Journal of Cancer, Volume 158, Issue 9, Page 2209-2218, 1 May 2026.
What's new? Although gastric carcinoma with neuroendocrine differentiation (GCNED) is associated with more aggressive features than conventional GC, its prognosis and survival remain poorly defined. To better understand survival patterns, the authors of the present study examined clinicopathological and prognostic features of GCNED patients following ...
Jinjin Li, Chenglong Wang, Yifan Shen, Zhen Huang, Jun Zhang, Siqi Rao, Youde Cao, Jiang Min   +7 more
wiley   +1 more source

Sobel-LBP [PDF]

2008 15th IEEE International Conference on Image Processing, 2008
Sanqiang Zhao, null Yongsheng Gao, Baochang Zhang   +2 more
openaire   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh, Ruchi Kakar, Seline Torkamboor, Yue Sun   +3 more
wiley   +1 more source

Impact of Positive Lifestyle Behaviors on Direct Health Care Cost Savings for Low Back Pain

Arthritis Care &Research, Volume 78, Issue 4, Page 537-546, April 2026.
Objective This study aimed to investigate the relationship between a previously purpose‐developed lifestyle behavior scale and health care cost savings related to low back pain (LBP). Methods This longitudinal study used data from the Australian Twin Back (AUTBACK) study. LBP and lifestyle behavior measures were collected at baseline. Physical activity
Ye Tian, Katharine E. Roberts, Michelle Hall, Paula R. Beckenkamp, Angelo Sabag, Karoline Moe, Ana Paula Carvalho‐e‐Silva, Emily J. Callander, Paulo H. Ferreira   +8 more
wiley   +1 more source

Genetic Diversity and Population Structure of Squalus cf. mitsukurii (Chondrichthyes: Squalidae) Revealed by ddRAD Sequencing

Animal Genetics, Volume 57, Issue 2, April 2026.
ABSTRACT Assessing genetic structure across ocean basins is essential to understand connectivity and guide conservation in data‐deficient open‐water sharks. In this study, we examined the population genomics of Squalus cf. mitsukurii by analyzing tissue samples collected from two distant regions: California, USA (Pacific Ocean) and Pernambuco, Brazil ...
Aisni Mayumi Corrêa de Lima Adachi, Ailton Amarante Ariza, Giovana da Silva Ribeiro, Pollyana Christine Gomes Roque, Matheus Marcos Rotundo, Marcelo Vianna, Gabriela Delpiani, Sergio Matias Delpiani, Juan Martín Díaz de Astarloa, Claudio Oliveira, Fausto Foresti, Vanessa Paes da Cruz   +11 more
wiley   +1 more source

Profiling Ten RHO GTPases in Myeloid Malignancies Reveals Distinct Expression Patterns and Prognostic Associations

Cancer Medicine, Volume 15, Issue 4, April 2026.
Expression of RHO GTPases in myeloid malignancies. Gene expression analysis of ten RHO GTPases revealed RHOBTB2, RND2, and RHOQ as differently expressed in patients with MDS and/or AML. RHOBTB2 was identified as a promising prognostic indicator. BM, bone marrow. MDS, myelodysplastic neoplasm. AML, acute myeloid leukemia.
Beatriz de Almeida Rodrigues, Luciana Bueno de Paiva, Maria Carolina Clares Ramalho, Amanda Ferreira Damasceno, Sara Teresinha Olalla Saad, Mariana Lazarini   +5 more
wiley   +1 more source