Results 141 to 150 of about 62,435 (224)

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche, Namdev More, Tiffany Lee, Mia Orr, Anne Camus, Devina Purmessur, Sarah E. Gulbrand, Nadeen O. Chahine, Lara Silverman, Dmitriy Sheyn   +9 more
wiley   +1 more source

Extraction method, structure-activity relationship and anti-tumor mechanism of <i>Lycium barbarum</i> polysaccharides. [PDF]

RSC Adv
Huang S, Huang G.
europepmc   +1 more source

Human In Vivo Disc Mechanics in Flexion, Extension, and Diurnal Loading With Aging and Degeneration

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background The intervertebral disc serves a critical role in spine function, but with aging and degeneration the disc undergoes changes that alter disc mechanics, and degeneration is often implicated in low back pain. The objective of this study was to quantify and evaluate the impact of aging and degeneration on in vivo lumbar disc mechanics ...
Harrah R. Newman, John M. Peloquin, Edward J. Vresilovic, Dawn M. Elliott   +3 more
wiley   +1 more source

Are Ceramic Cages an Option for Lumbar Interbody Fusion? A Comparative Biomechanical Numerical Study

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background The treatment of severe disc pathologies through lumbar interbody fusion (LIF) involves the insertion of an interbody cage into the degenerated disc space, together with a supporting fixation system. Conventional cage materials, such as Ti6Al4V and PEEK, present several limitations, most notably their non‐biodegradability ...
Davide Ninarello, Luigi La Barbera
wiley   +1 more source

Dietary <i>Lycium barbarum</i> Polysaccharides Support Retinal Redox Homeostasis Through Gut Microbiota-Associated Metabolic Modulation. [PDF]

Food Sci Nutr
Yang Y, Peng J, Li D, Zhou P, Wang Y, Xu J, Tan H, Deng Y, Peng Q.   +8 more
europepmc   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

MedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying, Huilin Wang, Xiu Lu, Wenjuan Zhang, Zhehao Lin, Kai Wang, Shangxuan Li, Lu Chen, Mingchao Jiang, Sarkawt Hamad, Yi Wang, Jianmin Wu, Shukuan Ling   +12 more
wiley   +1 more source

Dietary <i>Lycium barbarum</i> Polysaccharide Supplementation Modulates Serum Metabolomic Profiles and Gut Microbiota in Felines. [PDF]

Animals (Basel)
Zhang X, Yang H, Liu X, Tian W, Pu L, Hong L, Qin R, Ning Z, Zhang J.   +8 more
europepmc   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Frailty and Incident Low Back Pain in Middle-Aged and Older Adults: Longitudinal Evidence and Genetic Triangulation. [PDF]

J Pain Res
Lv H, Yang X, Guo Y, Chen H, Liao S, Quan Z, Yang C, Zhang Z.   +7 more
europepmc   +1 more source

Prevalence of Low Back Pain and Associated Factors Among Family Caregivers of Patients With Disabilities in Shenzhen, China: A Cross‐Sectional Study Based on Binary Logistic Regression Modelling

Nursing Open, Volume 13, Issue 9, September 2026.
ABSTRACT Aim To examine the prevalence of low back pain among family caregivers of patients with disabilities and identify its associated factors. Design Cross‐sectional study. Methods From May to August 2023, 209 family caregivers of patients with disabilities were recruited from four tertiary hospitals using convenience sampling.
Yu‐Jiao Sun, Li Dai, Jiao Xiong, Su Liang   +3 more
wiley   +1 more source