Results 161 to 170 of about 62,435 (224)

Harnessing Metabolic Priming to Engineer Human Nucleus Pulposus Macromass Overcoming Scalability‐Phenotype Tradeoff

open access: yesCell Proliferation, Volume 59, Issue 9, September 2026.
Human platelet lysate acts as a metabolic primer for hNPCs, enhancing fatty acid oxidation to drive proliferation while preserving phenotype. This enables construction of high‐quality, large‐size macromasses without necrotic defects, demonstrating exceptional efficacy in repairing degenerated discs in situ and providing a novel paradigm for ...
Yingbo Wang   +14 more
wiley   +1 more source

Cervical Small Cell Neuroendocrine Carcinoma Initially Detected on Cytology: Diagnostic Pitfalls and Clues

open access: yesCytopathology, Volume 37, Issue 5, Page 555-559, September 2026.
This case describes the initial detection of cervical small cell neuroendocrine carcinoma on conventional endometrial and cervicovaginal liquid‐based cytology. Given its rarity and high aggressiveness, early recognition and rapid, intensive treatment are crucial for improving patient outcomes.
Yesul Jeong
wiley   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

open access: yesThe FEBS Journal, Volume 293, Issue 18, Page 5558-5584, September 2026.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh   +7 more
wiley   +1 more source

Phylogeographic Patterns of the Eigenmannia humboldtii Group Shaped by Miocene‐Pleistocene Transitions

open access: yesJournal of Biogeography, Volume 53, Issue 9, September 2026.
ABSTRACT Aim Eigenmannia is a monophyletic genus of small and medium‐sized fishes known as ‘glass knifefishes’, with a wide distribution throughout the Neotropical region and a complex taxonomic history. This study aimed to investigate the phylogenetic diversification patterns within the Eigenmannia humboldtii species group (specifically E. nigra and E.
Weverton John P. Santos   +8 more
wiley   +1 more source

Intradiscal Delivery of Notoginsenoside R1‐Loaded PLGA Nanoparticles Attenuates Intervertebral Disc Degeneration in Rats

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.
ABSTRACT Intervertebral disc degeneration (IVDD) contributes to persistent low back pain, but existing treatments focus on symptom relief rather than addressing the degeneration. Notoginsenoside R1 (NR1), a bioactive saponin derived from Panax notoginseng, has exhibited protective effects in experimental models of disc injury.
Baichuan Zheng   +9 more
wiley   +1 more source

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