Results 91 to 100 of about 24,164 (284)

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Evaluation of the Biological Effect of a Nicotinamide-Containing Broad-Spectrum Sunscreen on Photodamaged Skin [PDF]

Introduction: UVA-UVB increases skin matrix metalloproteinases and breaks down extracellular proteins and fibrillar type 1 collagen, leading to photodamage. Topical application of nicotinamide prevents UV-induced immunosuppression.
Alejo B., Bague J., Calbet-Llopart N., Cinotti E., Del Marmol V., Demessant-Flavigny A. L., Espinosa N., Fontaine M., Iglesias P., Le Floc'h C., Malvehy J., Mateu J., Miyamoto M., Monnier J., Orte Cano C., Perez-Anker J., Perrot J. L., Potrony M., Prieto L., Puig S., Roses-Gibert P., Rubegni P., Suppa M., Tell-Marti G., Tognetti L., Torres-Moral T.   +25 more
core   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

Diversity, Distribution and Evolution of the Planktonic Diatom Family Chaetocerotaceae [PDF]

, 2017
The number and abundance of diatom species in environmental samples are counted traditionally by means of light microscopy (LM). However, recognizing –let alone, counting- species is often challenging because of the existence of cryptic species and ...
Gaonkar, Chetan Chandrakant
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Line-Field Confocal Optical Coherence Tomography for the Diagnosis of Skin Tumors: A Systematic Review and Meta-Analysis

Diagnostics
A line-field confocal optical coherence tomography (LC-OCT) combines confocal microscopy and optical coherence tomography into a single, rapid, easy-to-use device.
Shazli Razi, Yen-Hong Kuo, Gaurav Pathak, Priya Agarwal, Arianna Horgan, Prachi Parikh, Farah Deshmukh, Babar K. Rao   +7 more
doaj   +1 more source

A study to analyze six band multispectral images and fabricate a Fourier transform detector [PDF]

An automatic Fourier transform diffraction pattern sampling system, used to investigate techniques for forestry classification of six band multispectral aerial photography is presented.
Shackelford, R. G., Walsh, J. R., Jr.
core   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Impact of Elevated Intraocular Pressure on Lamina Cribrosa Oxygenation: A Combined Experimental–Computational Study on Monkeys

Ophthalmology Science
Purpose: To evaluate how lamina cribrosa (LC) oxygenation is affected by tissue distortions resulting from elevated intraocular pressure (IOP). Design: Experimental study on 4 monkeys, histology, and computational analysis.
Yuankai Lu, PhD, Yi Hua, PhD, Bingrui Wang, PhD, Qi Tian, Fuqiang Zhong, PhD, Andrew Theophanous, Shaharoz Tahir, Po-Yi Lee, PhD, Ian A. Sigal, PhD   +8 more
doaj   +1 more source

Diagnosis and therapy of actinic keratosis [PDF]

Actinic keratosis (AK) is considered a chronic and recurring in situ skin neoplasia, with a possible transformation into invasive squamous cell carcinoma (SCC).
Schuh, Sandra, Thamm, Janis Raphael, Welzel, Julia   +2 more
core   +1 more source