Results 211 to 220 of about 12,462,002 (332)
Clinicopathologic Disease Characteristics and Their Association with Adjuvant Chemotherapy Outcomes in Pulmonary Large-Cell Carcinoma Patients with or Without Neuroendocrine Features. [PDF]
Bayram D +8 more
europepmc +1 more source
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu +10 more
wiley +1 more source
Business model development at low-cost and full-service airlines throughout the years has led to a departure from the original models. The low-cost model is shifting up-market to capture higher yield traffic, while the full-service model is adopting low-cost model elements to achieve optimization.
openaire +1 more source
Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa +4 more
wiley +1 more source
Side-Specific Prognostic Factors in Colon Cancer: A Retrospective Analysis of Right- and Left-Sided Tumors. [PDF]
Serafin M +5 more
europepmc +1 more source
We present the first documentation of whitings in the Red Sea, observed in a lagoonal environment. These events are linked to cascading offshore dense waters that liberate trapped sea floor nutrients, triggering algal blooms and elevating alkalinity, which is buffered by direct CaCO3 precipitation—contributing to the accumulation of aragonite mud in ...
Manuel Ariza‐Fuentes +8 more
wiley +1 more source
Sidedness matters: Colon cancer outcomes in low-resource settings. [PDF]
González-Montero J +3 more
europepmc +1 more source
Nexus of Whey Proteins, Gut Dysbiosis, and Colonic Health
Whey proteins possess antimicrobial and prebiotic properties that modulate gut microbiota by promoting beneficial bacteria like Bifidobacterium while suppressing pathogens. This modulation enhances short‐chain fatty acid production and strengthens intestinal barrier integrity, potentially alleviating dysbiosis‐related conditions such as colitis and ...
Tolulope Joshua Ashaolu +4 more
wiley +1 more source
Leukoencephalopathy, brain calcifications, and cysts (LCC): Two unique cases. [PDF]
Grafstein J +7 more
europepmc +1 more source
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz +12 more
wiley +1 more source

