Results 11 to 20 of about 12,210 (188)
Fat Malabsorption and Ursodeoxycholic Acid Treatment in Children With Reduced Organic Solute Transporter-α (SLC51A) Expression. [PDF]
Objectives: A bile acid homeostasis disorder was suspected in 2 siblings and their second cousin who presented in infancy with fat malabsorption, severe fat‐soluble vitamin deficiency, rickets, and mild liver involvement. Our aims were to identify the genetic cause, describe the disease, and evaluate the response to ursodeoxycholic acid (UDCA ...
Tronstad RR +10 more
europepmc +2 more sources
Stromatolitic Mounds in Tidal-Facies Sandstones of the Paleoarchean Moodies Group (Barberton Greenstone Belt, Eswatini). [PDF]
ABSTRACT Shallow‐marine environments are thought to have been pivotal to the spreading, perhaps even the origin, of early life on Earth. The shallow‐marine Archean sedimentary record of early life, however, is biased towards carbonates; nearshore siliciclastic environments have not received proportional attention.
Reimann S +6 more
europepmc +2 more sources
A two-year prospective study assessing the performance of fetal chromosomal microarray analysis and next-generation sequencing in high-risk pregnancies. [PDF]
Abstract Background Introduction of cell‐free fetal DNA (cff‐DNA) testing in maternal blood opened possibilities to improve the performance of combined first‐trimester screening (cFTS) in terms of better detection of trisomies and lowering invasive testing rate.
Ridnõi K +12 more
europepmc +2 more sources
LCSH and Environmental Science
The environmental sciences are characterized by their boundless interdisciplinarity and cannot be discussed independently from other scientific fields such as ecology, engineering, and climatology. The complex nature of the discipline leads to challenges in placing it within a controlled vocabulary such as the Library of Congress Subject Headings (LCSH)
Frances Purcell, Julia Bullard
openaire +1 more source
LCSH, FAST Y DELICIOUS: VOCABULARIOS NORMALIZADOS Y NUEVAS FORMAS DE CATALOGACIÓN TEMÁTICA
Los vocabularios normalizados han sido las piezas medulares de la investigación bibliográfica, pero hay quienes consideran que los epígrafes organizados en cadenas de palabras son difíciles de comprender y utilizar.
Marilyn Montalvo Montalvo
doaj +2 more sources
The Library of Congress has been exploring “linked data” for over 10 years. The genesis of this development goes back to the W3C projects in the late 1990s on SGML, then XML, HTML, and finally a linked data oriented format RDF.
Sally McCallum
doaj +9 more sources
Continuous biopolymer production from biogas using feast‐famine strategies was found to be negatively impacted by the bacterial growth on the biopolymer during the feast phase. In this work, Rodriguez and colleagues investigated for the first time the potential of a novel two‐stage growth‐accumulation system to maximize the continuous production of CH4‐
Yadira Rodríguez +3 more
wiley +1 more source
Abstract Dissolved iron (dFe) transported by the Amur River greatly contributes to phytoplankton growth in the Sea of Okhotsk. Nevertheless, there has been little research on the source of dFe to rivers, especially in the Amur‐Mid Basin, which is situated in a sporadic permafrost area.
Y. Tashiro +5 more
wiley +1 more source
Abstract We describe an experiment where cattle urine was applied at a rate of 420 kg N ha−1, equivalent to 10 L m−2, to mesocosm swards of a high lipid genetically modified perennial ryegrass line (HME) and its wild type (WT). We measured N pools and fluxes in the plant and soil, soil microbial populations and N2O production.
Saman Bowatte +9 more
wiley +1 more source
Aldehyde‐Based Inhibitors of the Peptidoglycan O‐Acetylesterase Ape
Aldehyde‐based inhibitors of the peptidoglycan deacetylase Ape were shown to act as competitive inhibitors with Ki values in the low micromolar range. Reduction of the aldehyde to an alcohol abolishes inhibition, suggesting that the binding may involve the formation of a tetrahedral adduct with the active site serine nucleophile.
Dmytro Voskoboinyk +4 more
wiley +1 more source

