Results 1 to 10 of about 1,386 (133)

Preparation and Evaluation of Long-Acting Injectable Levocetirizine Prodrug Formulation [PDF]

Pharmaceutics
Background/Objectives: Levocetirizine (LCZ) is a second-generation antihistamine with minimal central nervous system effects. However, its short half-life necessitates daily dosing, potentially reducing adherence in pediatric populations.
Jun-hyun Ahn
doaj   +2 more sources

Luliconazole-loaded nanostructured lipid carrier: formulation, characterization, and in vitro antifungal evaluation against a panel of resistant fungal strains [PDF]

Scientific Reports
Luliconazole (LCZ) is a topical imidazole antifungal agent with broad-spectrum activity. However, LCZ encounters challenges such as low aqueous solubility, skin retention, and penetration, which reduce its dermal bioavailability and hinder its efficacy ...
Mohsen Nosratabadi, Seyyed Mobin Rahimnia, Robab Ebrahimi Barogh, Mahdi Abastabar, Iman Haghani, Javad Akhtari, Zohreh Hajheydari, Pedram Ebrahimnejad   +7 more
doaj   +2 more sources

Efficacy Evaluation of Luliconazole-Loaded Nanostructured Lipid Carriers in Treatment-Resistant Dermatophytosis: A Randomized Clinical Trial. [PDF]

Mycoses
ABSTRACT Background Dermatophytosis is a common superficial fungal infection that is increasingly complicated by terbinafine (TRB)‐resistant strains, especially Trichophyton indotineae. Conventional antifungals often show limited efficacy against resistant isolates, highlighting the need for novel treatments.
Barogh RE, Jeddi SA, Rokni GR, Fam HMT, Raeisabadi A, Yahyazadeh Z, Rahimnia SM, Ebrahimnejad P, Nazar E, Gholizadeh N, Haghani I, Nosratabadi M, Kazeminejad A, Javidnia J, Hedayati MT, Meis JF, Al-Harrasi A, Abastabar M, Al-Hatmi AMS.   +18 more
europepmc   +2 more sources

Development of a Luliconazole Nanoemulsion as a Prospective Ophthalmic Delivery System for the Treatment of Fungal Keratitis: In Vitro and In Vivo Evaluation

Pharmaceutics, 2022
Luliconazole (LCZ), a novel imidazole drug, has broad-spectrum and potential antifungal effects, which makes it a possible cure for fungal keratitis; nevertheless, its medical use in ocular infections is hindered by its poor solubility.
Jingjing Yang, Zhen Liang, Ping Lu, Fei Song, Zhen Zhang, Tianyang Zhou, Jingguo Li, Junjie Zhang   +7 more
doaj   +1 more source

Air Humidity Characteristics in “Local Climate Zones” of Novi Sad (Serbia) Based on Long-Term Data

ISPRS International Journal of Geo-Information, 2021
This study aims to investigate spatial and temporal dynamics and relationship between air temperature and five air humidity parameters (relative humidity, water vapor pressure, absolute humidity, specific humidity, and vapor pressure deficit) in Novi Sad,
Jelena Dunjić, Dragan Milošević, Milena Kojić, Stevan Savić, Zorana Lužanin, Ivan Šećerov, Daniela Arsenović   +6 more
doaj   +1 more source

Spatial Variability and Temporal Heterogeneity of Surface Urban Heat Island Patterns and the Suitability of Local Climate Zones for Land Surface Temperature Characterization

Remote Sensing, 2021
This study investigated monthly variations of surface urban heat island intensity (SUHII) and the applicability of the local climate zones (LCZ) scheme for land surface temperature (LST) differentiation within three spatial contexts, including urban ...
Ziqi Zhao, Ayyoob Sharifi, Xin Dong, Lidu Shen, Bao-Jie He   +4 more
doaj   +1 more source

LCZ4r package R for local climate zones and urban heat islands [PDF]

Scientific Reports
Tiago Silva, Max Anjos, Ezequiel Correia   +2 more
exaly   +2 more sources

Avaliação dos efeitos microclimáticos de diferentes zonas climáticas locais em cidade de clima temperado

PARC: Pesquisa em Arquitetura e Construção, 2020
O clima urbano é influenciado por características morfológicas e de uso e ocupação do solo. Aspectos como grau de verticalização, presença de vegetação e adensamento urbano influenciam diretamente sobre variáveis climáticas, gerando microclimas ...
Eduardo Krüger, Natasha Hansen Gapski Pereira   +1 more
doaj   +1 more source

Inference of Local Climate Zones from GIS Data, and Comparison to WUDAPT Classification and Custom-Fit Clusters

Land, 2022
A GIS-based approach is used in this study to obtain a better LCZ map of Berlin in comparison to the remote-sensing-based WUDAPT L0 approach. The LCZ classification of land use/cover can be used, among other applications, to characterize the urban heat ...
Fadel Muhammad, Changkun Xie, Julian Vogel, Afshin Afshari   +3 more
doaj   +1 more source

Investigations of Surface Urban Heat Island Effect Based on Local Climate Zone Method: A Case of Xi'an [PDF]

E3S Web of Conferences, 2019
Urbanization seriously affects the urban climate and the quality of human settlement. Based on Landsat8 remote sensing and building vector data, local climate zone (LCZ) method is employed to study the influences of urban form on land surface temperature
Mu Kaikai, Liu Yan, Zhang Moyan, Han Bing, Yang Liu   +4 more
doaj   +1 more source