Results 171 to 180 of about 251,423 (287)
QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley +1 more source
Effects of L-Valine Supplementation in Low-Nitrogen Diets on Rumen Fermentation Parameters, Predicted Methane Emissions Production, and Microbial Communities In Vitro. [PDF]
Li C +6 more
europepmc +1 more source
Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee +4 more
wiley +1 more source
Characterization of Pulmonary Dysfunction in Systemic Juvenile Idiopathic Arthritis Using Xenon and Proton MRI. [PDF]
Garrison WJ +15 more
europepmc +1 more source

