Results 151 to 160 of about 260,119 (338)

Correlation between Absorption and Substitution of Photochromic 1,2‐Bis(thienyl)ethenes (BTEs) Using Modified Spectroscopic Hammett Equations

European Journal of Organic Chemistry, Volume 26, Issue 1, January 2, 2023., 2023
The Hammett‐Brown substituent constants of α'‐substituted BTEs (open and closed) correlate linearly with the excitation energies of the absorption maxima applying the spectroscopic Hammett equation. Abstract Series of photochromic 1,2‐bis(thienyl)ethenes possessing perfluorocyclopentene backbones, either hydrogen or methyl groups at the β‐positions of ...
Sven Nagorny, Thea Weingartz, Jan C. Namyslo, Jörg Adams, Andreas Schmidt   +4 more
wiley   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

Angewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu, Xiaocao Ma, Jingguo Wang, Tiantian Chen, Jiahui Yang, Yan Liu, Zhun Lin, Minhao Wu, Tony Y. Hu, Yuanqing Zhang   +9 more
wiley   +2 more sources

Setenave-estaleiros navais de setúbal estacas de ancoragem nas docas 21 e 22

Geotecnia, 1975
Teixeira Duarte, Lda.
doaj   +1 more source

A direct LDA algorithm for high-dimensional data — with application to face recognition [PDF]

, 2001
Hua Yu, Jie Yang
openalex   +1 more source

Multi‐Risk‐Level Sarcopenia‐Prone Screening via Machine Learning Classification of Sit‐to‐Stand Motion Metrics from Wearable Sensors

Advanced Intelligent Systems, EarlyView.
A machine learning approach utilizes micro inertial measurement units (μIMUs) for noninvasive sarcopenia screening through a sit‐to‐stand test. With 53 older participants wearing IMUs, 510 features are extracted across four motion phases. Five algorithms (support vector machine, K‐nearest neighbors, decision tree, linear discriminant analysis, and ...
Keer Wang, Hongyu Zhang, Clio Yuen Man Cheng, Meng Chen, King Wai Chiu Lai, Calvin Kalun Or, Yong Hu, Arul Lenus Roy Vellaisamy, Cindy Lo Kuen Lam, Ning Xi, Vivian Weiqun Lou, Wen Jung Li   +11 more
wiley   +1 more source

Enantioconvergent Deacylative Functionalization toward α‐Quaternary Nitriles

Angewandte Chemie, EarlyView.
An enantioconvergent quaternary‐to‐quaternary synthesis of α‐chiral nitriles has been enabled. By replacing the acyl group with a variety of allyl, propargyl, and benzyl motifs, the functional group swap can convert easily available β‐ketonitriles to assorted quaternary stereocenters en route to bioactive molecules of broad interests.
Minghao Zhang, Zhongxing Huang
wiley   +2 more sources

Cerebrospinal Fluid and Serum Neuron‐Specific Enolase in Niemann‐Pick Disease Type C1

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Niemann‐Pick disease, type C1 (NPC1) is an ultra rare, autosomal recessive disorder characterized by impaired intracellular cholesterol trafficking. This study assessed neuron‐specific enolase (NSE) as a biomarker for disease status and treatment response in individuals with NPC1.
Cameron J. Padilla, Derek M. Alexander, Desiree A. Labor, Orsolya K. Albert, Kendall P. Robbins, Elizabeth Berry‐Kravis, Forbes D. Porter   +6 more
wiley   +1 more source

Size‐Programmable Matteson‐Type Annulation: Construction of Spirocycles from Simple Cyclic Ketones

Angewandte Chemie, EarlyView.
An iterative boron‐homologation approach is developed to enable programmable syntheses of various carbocycles with different sizes stereoselectively from simple precursors. This method utilizes an electron‐withdrawing group (EWG) as a handle to enable intramolecular Matteson‐type couplings, leading to diastereoselective and enantioselective ring ...
Woohyun Jo, Juliane K. Scholz, Hairong Lyu, Seung Hwan Cho, Guangbin Dong   +4 more
wiley   +2 more sources

Elexacaftor–Tezacaftor–Ivacaftor Improves Sinonasal Outcomes in Young Children With Cystic Fibrosis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Severe chronic rhinosinusitis (CRS) is a near universal manifestation of cystic fibrosis. Elexacaftor/tezacaftor/ivacaftor (ETI) is an oral, small molecule, highly effective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) corrector–potentiator drug.
Amanda L. Stapleton, Adam Kimple, Jennifer L. Goralski, Daniel M. Beswick, Anshika Gupta, Douglas A. Li, Barton F. Branstetter, S. Mehdi Nouraie, Amber D. Shaffer, Brent Senior, Anna C. Zemke   +10 more
wiley   +1 more source

Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances

Animal Models and Experimental Medicine, EarlyView.
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong, Meiru Jiang, Kun Yuan, Fang Sheng, Xiuyun Xu, Yong Cui, Xijia Sun, Wenfei Tan   +7 more
wiley   +1 more source