Results 131 to 140 of about 2,408 (179)
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An update on LDL apheresis for nephrotic syndrome
Pediatric Nephrology, 2018Low-density lipoprotein (LDL) apheresis has been used increasingly in clinical practice for the treatment of renal diseases with nephrotic syndrome (NS), specifically focal segmental glomerulosclerosis (FSGS). Persistent hyperlipidemia for prolonged periods is nephrotoxic and leads to chronic progressive glomerular and tubulointerstitial injury ...
Rupesh Raina, Vinod Krishnappa
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Applications of LDL-apheresis in nephrology
Clinical and Experimental Nephrology, 2008LDL-apheresis (LA) was originally used for familial hyperlipidemia, and then in Japan extended to use for the treatment of patients with peripheral arterial disease (PAD) and nephrotic syndrome due to steroid-resistant focal glomerular sclerosis (FGS). The reason why this treatment is applicable for these disorders is due to the fact that LA exerts its
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Recommendations for the use of LDL apheresis
Atherosclerosis, 2008Plasma exchange has been shown to increase life-expectancy in homozygous familial hypercholesterolaemia (FH) but increasingly is being replaced by LDL apheresis. Several methods are now available for undertaking this procedure, which lowers LDL cholesterol and Lp(a) efficiently and safely when performed weekly or bi-weekly and causes only slight ...
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Activation of coagulation by a LDL-apheresis device
Blood Coagulation & Fibrinolysis, 1996LDL-apheresis often induces an almost constant and progressive increase of the differential pressure of plasma flowing through the dextran sulphate cellulose column, reducing the efficacy of the treatment. On two occasions we were able to identify a fibrin plug by immunofluorescence. Our aim was to verify the modification of some coagulation indicators
C, Giansante +7 more
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Role of LDL apheresis in the management of hypercholesterolaemia
Transfusion Science, 1993Abstract It is now established that extracorporeal cholesterol removal is the best means of improving prognosis in patients with homozygous FH and this should be started before atherosclerosis becomes apparent. Anti-human LDL antibodysepharose columns, dextran sulphate-cellulose gel columns and the HELP system are all potent methods of extracorporeal
Y, Kitano, G R, Thompson
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Overview: Techniques and Indications of LDL-Apheresis
Biomaterials, Artificial Cells and Immobilization Biotechnology, 1991In recent years, LDL-apheresis has emerged to be an efficient treatment of hyperlipidemia in patients who do not respond sufficiently to diet and lipid lowering drugs. A survey of LDL lowering extracorporeal procedures is presented. Among them, to date 5 procedures have been used clinically on a routine basis: unselective plasma exchange, semi ...
T, Bosch, H J, Gurland
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Organization and Technical Problems of LDL-apheresis
The International Journal of Artificial Organs, 1993The Authors consider problems related to technique and organization of LDL-Apher-esis with respect to some particular aspects. They evaluate: a) Technical complexity of procedures both in devices to use and in staff preparation; b) Length of treatment which conditions the other fields of activity; c)
N, Scarpato +3 more
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[Plaque stabilization by LDL apheresis?].
Herz, 1999Vulnerable lipid-rich plaques are often the cause of atherothrombotic events leading to unstable angina and/or to acute myocardial infarction. Consequent long-term LDL-lowering by drugs as shown by the most important intervention studies lead to plaque stabilization as shown by the significant reduction of myocardial reinfarction.
P, Schuff-Werner, V, Schettler
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[LDL apheresis: an update and overview. LDL apheresis in Sardinia, Italy (SMILDLa)].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2012LDL apheresis (LDLa) is an invasive therapeutic tool to control qualitative and quantitative disorders of lipid metabolism. It is aimed at achieving a metabolic balance in association with lipid-lowering drugs in patients with severe, genetically determined or acquired dyslipidemia who do not reach clinically adequate LDL-cholesterol (LDL-C) levels (
Claudia, Stefanutti +2 more
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LDL apheresis as it relates to nursing practice
Transfusion and Apheresis Science, 2017Nurses are an essential partner in the treatment of complex diseases and they have extensive influence on patient outcomes. Connecting a patient to a machine takes courage, skill, and a whole lot of trust. Anyone who has earned the title of "nurse" has shown courage. Skill comes with hours and hours of practice. Trust is earned and ongoing.
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