Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen +7 more
wiley +1 more source
Low Serum LDL-C Is Associated with Poorer Overall Survival and Lipid-Related Molecular Features in Colorectal Cancer. [PDF]
Wang J, Hsieh Y, Wang W, Xu J.
europepmc +1 more source
Abstract Background Epilepsy is a serious chronic brain disease. However, limited study is focused on the association between dietary pattern and epilepsy management. Hence, we aim to investigate the association between the Healthy Eating Index (HEI‐2020) and epilepsy odds.
Kun Yu, Yingxin Wang, Huaiqing Gao
wiley +1 more source
Sex disparities in LDL-C target achievement among older adults receiving statin therapy. [PDF]
Nguyen HLH, Pham ATN, Tran TT.
europepmc +1 more source
The effect of anti‐seizure medications on exposure to statins: A systematic review and meta‐analysis
Abstract Objectives Antiseizure medications (ASMs) can reduce the efficacy of statin treatment, partly due to reduction in statin concentrations. In this systematic review and network meta‐analysis (NMA), we compared the effects of ASMs and the prototypical enzyme inducer rifampin on statin exposure.
Sharon Valiyev Huino +5 more
wiley +1 more source
Subgroup-Specific Nomogram for Refined Risk Stratification in Hepatocellular Carcinoma Patients with Low LDL-C. [PDF]
Liu B, Gu Z, Li L, Li L, Jin R, Hu C.
europepmc +1 more source
Abstract Objective Dietary therapy is an effective treatment for drug‐resistant epilepsy; however, low adherence presents a significant barrier to use in the clinical setting. This study aims to evaluate a multimodality digital health intervention to overcome this barrier and improve outcomes in adults undertaking the modified ketogenic diet for ...
Neha Kaul +18 more
wiley +1 more source
Profound Hypothyroidism as a Reversible Cause of Severe Low-Density Lipoprotein Cholesterol (LDL-C) Elevation: A Case Report. [PDF]
Mataraarachchi NE, Bhat S.
europepmc +1 more source
ABSTRACT Background Physical activity is common in patients with anorexia nervosa (AN), who often reported symptoms consistent with exercise dependence. Craving, the subjective urge to engage in a specific behaviour, is an important mechanism in the development of addiction and could be triggered by cues from the environment.
Giammarco Cascino +8 more
wiley +1 more source
Suboptimal Achievement of Guideline-Recommended LDL-C Targets in Older Patients Undergoing Comprehensive Geriatric Care. [PDF]
Fleisher I +5 more
europepmc +1 more source

