LDLCHOLESTEROLEXAMINATION (LDL-C) USINGHOMOGENEOUS ASSAY
Homogeneous method describe as a method that does not require separation of free and bound label. This method has the ability tofully automate the determination of LDL-C directly small sample volume sand short examination time.
Made DwiAmbara Putra
doaj +1 more source
PCSK9 and LDL-C: The Role of Exercise [PDF]
s Purpose Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) is a pivotal regulator of low lipoprotein-cholesterol (LDL-C) and LDL receptor (LDLR) metabolism, and the interest in PCSK9 has increased in cardiovascular diseases.
Jaeho Jin +3 more
doaj +1 more source
Measurement of low‐density lipoprotein cholesterol levels in primary and secondary prevention patients: Insights from the PALM registry [PDF]
Background The 2013 American College of Cardiology/American Heart Association Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults recommended testing low-density lipoprotein cholesterol ( LDL -C) to ...
Goldberg, Anne C +11 more
core +2 more sources
Comparison between Values of Low Density Lipoprotein Cholesterol as Estimated by Direct Enzymatic Method with Calculated Methods Applying Friedewald’s Equation and Novel’s Equation: A Cross-sectional Study [PDF]
Introduction: Lipid profile is routinely used as a screening test to identify the risk of Cardiovascular Diseases (CVD). Elevated Low Density Lipoprotein cholesterol (LDL-c) is an important modifiable risk factor of atherosclerotic CVD.
Maithri Chikkabasavanahalli Manjegowda +3 more
doaj +1 more source
Systematic review and network meta-analysis on the efficacy of evolocumab and other therapies for the management of lipid levels in hyperlipidemia [PDF]
Background: The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors evolocumab and alirocumab substantially reduce low‐density lipoprotein cholesterol (LDL‐C) when added to statin therapy in patients who need additional LDL‐C reduction ...
Bray, Sarah +13 more
core +1 more source
OBJETIVO: Avaliar a dosagem direta do colesterol LDL (LDL-C) por um método homogêneo, em comparação com a estimativa pela fórmula de Friedewald, em uma grande população heterogênea.
Caio Maurício Mendes de Cordova +3 more
doaj +1 more source
Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M +25 more
core +2 more sources
Low LDL-C and High HDL-C Levels Are Associated with Elevated Serum Transaminases amongst Adults in the United States: A Cross-sectional Study [PDF]
Background: Dyslipidemia, typically recognized as high serum triglyceride, high low-density lipoprotein cholesterol (LDL-C) or low high-density lipoprotein cholesterol (HDL-C) levels, are associated with nonalcoholic fatty liver disease (NAFLD). However,
Jiang, Zhenghui Gordon +4 more
core +11 more sources
Effect of gestational diabetes mellitus on lipid profile: A systematic review and meta-analysis
Gestational diabetes mellitus (GDM) can have adverse effects on pregnancy. GDM is associated with changes in the lipid profile of pregnant women. Finding out the early ways to diagnose GDM can prevent the adverse outcomes.
Rahnemaei Fatemeh Alsadat +4 more
doaj +1 more source
Evidence-based goals in LDL-C reduction [PDF]
The evidence from trials of statin therapy suggests that benefits in cardiovascular disease (CVD) event reduction are proportional to the magnitude of low-density lipoprotein cholesterol (LDL-C) lowering. The lack of a threshold at which LDL-C lowering is not beneficial, in terms of CVD prevention observed in these trials, is supported by ...
Soran, Handrean +2 more
openaire +2 more sources

