Results 191 to 200 of about 3,049 (238)
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Recommendations for the use of LDL apheresis
Atherosclerosis, 2008Plasma exchange has been shown to increase life-expectancy in homozygous familial hypercholesterolaemia (FH) but increasingly is being replaced by LDL apheresis. Several methods are now available for undertaking this procedure, which lowers LDL cholesterol and Lp(a) efficiently and safely when performed weekly or bi-weekly and causes only slight ...
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Activation of coagulation by a LDL-apheresis device
Blood Coagulation & Fibrinolysis, 1996LDL-apheresis often induces an almost constant and progressive increase of the differential pressure of plasma flowing through the dextran sulphate cellulose column, reducing the efficacy of the treatment. On two occasions we were able to identify a fibrin plug by immunofluorescence. Our aim was to verify the modification of some coagulation indicators
Nicola Fiotti+7 more
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Organization and Technical Problems of LDL-apheresis
The International Journal of Artificial Organs, 1993The Authors consider problems related to technique and organization of LDL-Apher-esis with respect to some particular aspects. They evaluate: a) Technical complexity of procedures both in devices to use and in staff preparation; b) Length of treatment which conditions the other fields of activity; c) Problems in management treatments periodicity ...
Formisano S+3 more
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LDL Apheresis and Inflammation – Implications for Atherosclerosis
Scandinavian Journal of Immunology, 2012AbstractLow‐density lipoprotein (LDL) apheresis is an extracorporeal treatment modality used in high‐risk patients when LDL cholesterol levels cannot be reduced adequately with medication. The treatment is highly effective, but could be affected by potential unwanted effects on pro‐ and anti‐inflammatory biomarkers.
Anders Hovland+2 more
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Role of LDL apheresis in the management of hypercholesterolaemia
Transfusion Science, 1993Abstract It is now established that extracorporeal cholesterol removal is the best means of improving prognosis in patients with homozygous FH and this should be started before atherosclerosis becomes apparent. Anti-human LDL antibodysepharose columns, dextran sulphate-cellulose gel columns and the HELP system are all potent methods of extracorporeal
Gilbert R. Thompson, Yuri Kitano
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Overview: Techniques and Indications of LDL-Apheresis
Biomaterials, Artificial Cells and Immobilization Biotechnology, 1991In recent years, LDL-apheresis has emerged to be an efficient treatment of hyperlipidemia in patients who do not respond sufficiently to diet and lipid lowering drugs. A survey of LDL lowering extracorporeal procedures is presented. Among them, to date 5 procedures have been used clinically on a routine basis: unselective plasma exchange, semi ...
Thomas C. G. Bosch, Hans J. Gurland
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LDL Apheresis in Atherosclerotic Disease with Hyperlipidemia
ASAIO Journal, 1992Low density lipoprotein (LDL) apheresis was carried out in 28 atherosclerotic patients with clinical signs of poor peripheral circulation and abnormally high LDL levels. The LDL apheresis using extracorporeal adsorption with a dextran sulfate cellulose column (Liposorber, Kaneka, Japan) was done 10 times over 3 months.
Tetsuzo Agishi+2 more
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LDL Apheresis: A Novel Technique (LIPOCOLLECT 200)
Artificial Organs, 2009AbstractTherapeutic means to lower Lp(a) are limited. The most effective method to reduce plasma Lp(a) concentration significantly is therapeutic apheresis, namely, low‐density lipoprotein (LDL) lipoprotein(a) (Lp(a)) apheresis. A novel technique based on reusable LDL adsorber called Lipocollect 200 (Medicollect, Rimbach, Germany) allows the removal of
STEFANUTTI, Claudia+3 more
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Effects of LDL apheresis on restenosis after angioplasty
Chemistry and Physics of Lipids, 1994We performed long-term maintenance LDL apheresis therapy on patients with hypercholesterolemia after undergoing PTCA, and investigated the therapeutic effects of reducing serum cholesterol, LDL-cholesterol and Lp(a). LDL apheresis significantly reduced serum lipids and was an efficacious therapy in the prevention of recurrent stenosis after PTCA.
Noboru Tekekoshi+2 more
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Efficacy criteria and cholesterol targets for LDL apheresis
Atherosclerosis, 2010Low density lipoprotein (LDL) apheresis is now accepted as the treatment of choice for patients with homozygous familial hypercholesterolaemia and for heterozygotes with cardiovascular disease refractory to lipid-lowering drug therapy. However, a paucity of evidence has meant that detailed guidance on the extent of cholesterol reduction required to ...
C. Tyler+14 more
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