Results 21 to 30 of about 111,529 (192)

Acute effects of low density lipoprotein apheresis on metabolic parameters of apolipoprotein B

Journal of Lipid Research, 2000
Apheresis is a treatment option for patients with severe hypercholesterolemia and coronary artery disease. It is unknown whether such therapy changes kinetic parameters of lipoprotein metabolism, such as apolipoprotein B (apoB) secretion rates ...
Klaus G. Parhofer, P. Hugh R. Barrett, Thomas Demant, Peter Schwandt   +3 more
doaj   +1 more source

Preoperative Low-Density Lipoprotein Apheresis for Preventing Recurrence of Focal Segmental Glomerulosclerosis after Kidney Transplantation

Journal of Transplantation, 2018
Background. Focal segmental glomerulosclerosis (FSGS) often develops rapidly and frequently progresses to renal failure, while the recurrence rate after kidney transplantation is 20–50%.
Akihito Sannomiya, Toru Murakami, Ichiro Koyama, Kosaku Nitta, Ichiro Nakajima, Shohei Fuchinoue   +5 more
doaj   +1 more source

Role of lipoprotein apheresis in the management of familial hypercholesterolemia

Global Journal of Transfusion Medicine, 2021
Familial Hypercholesterolemia (FH) is an autosomal dominant disorder due to a congenital absence of low-density lipoprotein receptor (LDL-R) that transports cholesterol-carrying lipoprotein particles into cells.
Shamanna Seshadri Iyengar, Ambuja Kantharaj, Chandrashekar Shivaram, D S Hemantha Kumara, Roopa Murgod, G Shreedhara   +5 more
doaj   +1 more source

Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy.

Journal of Lipid Research, 1994
To determine the acute and long-term effects of low density lipoprotein (LDL) reduction on cholesterol biosynthesis, we studied changes in the cholesterol precursors mevalonic acid (MVA) and lathosterol in patients with heterozygous familial ...
M Pfohl, R P Naoumova, C Klass, W Knisel, B Jakober, T Risler, G R Thompson   +6 more
doaj   +1 more source

THE IMPACT OF EVINACUMAB THERAPY ON PEDIATRIC PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: RESULTS FROM PART B OF A PHASE 3 TRIAL

American Journal of Preventive Cardiology, 2023
Therapeutic Area: ASCVD /CVD Risk Reduction Background: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated low-density lipoprotein cholesterol (LDL-C) levels.
Albert Wiegman, Susanne Greber-Platzer, Shazia Ali, Divya Singh, M. Doortje Reijman, Eliot A Brinton, Min-Ji Charng, Shubha Srinivasan, Carissa Baker-Smith, Seth Baum, Julie Brothers, Jacob Hartz, Patrick M. Moriarty, Poulabi Banerjee, Richard T George, Robert Pordy   +15 more
doaj   +1 more source

Beyond lipids: Systemic effects of lipoprotein apheresis. [PDF]

Transfusion
Transfusion, Volume 66, Issue 3, Page 590-598, March 2026.
Nadim M, Akgun Y.
europepmc   +2 more sources

Emerging low-density lipoprotein (LDL) therapies: Management of severely elevated LDL cholesterol—The role of LDL-apheresis [PDF]

, 2013
Low-density lipoprotein (LDL)-apheresis is a Food and Drug Administration–approved treatment for patients with homozygous familial hypercholesterolemia (FH) or severe heterozygous FH.
McGowan, Mary P.
core   +1 more source

Urinary Neopterin and Microalbuminuria in Patients Treated by Low-density Lipoprotein Apheresis

Pteridines, 2005
Low-density lipoprotein (LDL)-apheresis is a method of extracorporeal elimination of LDL-cholesterol in patients with severe primary lipoprotein disorders.
Cermanová Melanie, Melichar Bohuslav, Solichová Dagmar, Bláha Milan, Bláha Vladimir, Blazek Martin, Mašín Vladimir, Cerman Jaroslav, Zadák Zdenek   +8 more
doaj   +1 more source

Treatment of Homozygous Familial Hypercholesterolemia With EvinacumabNovel Teaching Points

CJC Open, 2022
Patients with homozygous familial hypercholesterolemia (HoFH) have extremely elevated levels of low-density lipoprotein cholesterol (LDL-C), with premature atherosclerosis and aortic valve disease.
Natasha Jeraj, BSc, Shih-Han S. Huang, MD, Brooke A. Kennedy, BSc, Robert A. Hegele, MD   +3 more
doaj   +1 more source

Low-density lipoprotein apheresis in a pediatric patient of familial hypercholesterolemia: Primi experientia from a tertiary care center in North India

Asian Journal of Transfusion Science, 2017
Familial hypercholesterolemia (FH) is an autosomal dominant disorder due to mutation of apolipoprotein-B receptor gene causing severe dyslipidemia. Lifestyle modification and medical treatment attenuate the disease progression, but as these fail to ...
Kanchan Dogra, Alpesh Goyal, Rajesh Khadgawat, Yashdeep Gupta, Diptiranjan Rout, Parag Prabhakar Fulzele, Rahul Chaurasia, Poonam Coshic, Kabita Chatterjee   +8 more
doaj   +1 more source